Evidence map›Paper›PMID 16832704›Full record

ArticleJournal of molecular histology2006

Expression of Bcl-2 and Bax protein in normal pineal gland in children and young adult.

Wiesław Marcol, Katarzyna Kotulska, Magdalena Larysz-Brysz, Izabela Malinowska-Kołodziej, Marek Mandera, Joanna Lewin-Kowalik

Abstract read
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Article in Journal of molecular histology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wiesław MarcolDepartment of Physiology, Medical University of Silesia, 18 Medyków, 40-752 Katowice, Poland. Vie@alpha.net.pl
Katarzyna Kotulska
Magdalena Larysz-Brysz
Izabela Malinowska-Kołodziej
Marek Mandera
Joanna Lewin-Kowalik
Medical University of Silesia · PLChildren's Memorial Health Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Bcl family contains both pro and antiapoptotic proteins participating in the regulation of neuronal cell death in several pathological conditions. However, very little is known about physiological profiles of Bcl-2/Bax expression in normal brain. In this study, we examined expression profile of Bcl-2 and Bax proteins in normal pineal gland in children. The material for analysis was obtained by biopsy of pineal parenchyma during surgery of pineal cysts. All specimens were labeled immunohistochemically and analyzed by means of confocal laser scanning microscope. We found only few Bcl-2 expressing (0.7%) and no Bax-immunopositive (0.0%) pinealocytes. Bcl-2-positive cells were mature neurons, neither young ones nor glia.

Indexed as

Adolescentbcl-2-Associated X ProteinBiomarkersBiopsyBrain DiseasesChildCystsFemaleFluorescent Antibody Technique, IndirectHumansMaleNeuronsPineal GlandProto-Oncogene Proteins c-bcl-2BAX protein, humanbcl-2-Associated X ProteinBiomarkersProto-Oncogene Proteins c-bcl-2

Identifiers

PMID16832704
OpenAlexW2126712117

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.