ArticleExtremophiles : life under extreme conditions2006
Correlation between codon usage and thermostability.
Article in Extremophiles : life under extreme conditions, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Complete Chloroplast Genome Sequence ofLife (Basel, Switzerland) · 2022Article
- Analysis of codon usage patterns in open reading frame 4 of hepatitis E viruses.Beni-Suef University journal of basic and applied sciences · 2022Article
- Tracing and exploring the evolutionary origin and systematic function of fish complement C9.Molecular genetics and genomics : MGG · 2021Article
- Deciphering the rationale behind specific codon usage pattern in extremophiles.Scientific reports · 2018Article
- Proteins of generalist and specialist pathogens differ in their amino acid composition.Life science alliance · 2018Article
- Genome-Wide Analysis of Codon Usage Bias in Epichloë festucae.International journal of molecular sciences · 2016Article
- Article
- ANCAC: amino acid, nucleotide, and codon analysis of COGs--a tool for sequence bias analysis in microbial orthologs.BMC bioinformatics · 2012Article
- Patterns and influencing factor of synonymous codon usage in porcine circovirus.Virology journal · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Variations of arginine codon usage between organisms may have important implications to thermostability. The preferential usage of AGR codons for arginine in thermophiles and hyperthermophiles implies positive error minimization, contributing to avoid mutations that could harm protein thermostability. This bias is not a mere consequence of increased G + C content, as it has been previously suggested, and may represent a new mechanism of adaptation to protein thermostability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.