BRCA1 and BRCA2 cancer risks.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers.Journal of the National Cancer Institute · 2009
   Pooled it
2. Longitudinal changes in patient distress following interactive decision aid use among BRCA1/2 carriers: a randomized trial.Medical decision making : an international journal of the Society for Medical Decision Making
   Trial
3. The Role of Race and Insurance Status in Access to Genetic Counseling and Testing Among High-Risk Breast Cancer Patients.The oncologist · 2022
   Article
4. Young Israeli women with epithelial ovarian cancer: prevalence of BRCA mutations and clinical correlates.Journal of gynecologic oncology · 2017
   Article
5. Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil.Genetics and molecular biology · 2016
   Article
6. Breed-predispositions to cancer in pedigree dogs.ISRN veterinary science · 2013
   Article
7. Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression.Cancer prevention research (Philadelphia, Pa.) · 2011
   Article
8. Posttranscriptional regulation of miRNAs in the DNA damage response.RNA biology
   Article

Corrections and comments

• Comment on
  Characterization of BRCA1 and BRCA2 mutations in a large United States sample.2006

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as