ArticleClinical and vaccine immunology : CVI2006
Innate immune response to Anaplasma phagocytophilum contributes to hepatic injury.
Article in Clinical and vaccine immunology : CVI, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Evaluation of serum levels of CRP and TNF-α in dogs infected withOpen veterinary journal · 2025Article
- Enhanced Production of IL-10 in PCR-Positive Dogs Infected withMicroorganisms · 2024Article
- Innate immunity in rickettsial infections.Frontiers in cellular and infection microbiology · 2023Review
- Epidemiological and Clinicopathological Features ofFrontiers in veterinary science · 2021Review
- Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria.Zoonoses (Shannon, Ireland) · 2021Article
- Immunization against Anaplasma phagocytophilum Adhesin Binding Domains Confers Protection against Infection in the Mouse Model.Infection and immunity · 2020Article
- Article
- Differential Susceptibility of Male Versus Female Laboratory Mice toTropical medicine and infectious disease · 2018Article
- A hybrid protein containing MSP1a repeats and Omp7, Omp8 and Omp9 epitopes protect immunized BALB/c mice against anaplasmosis.Veterinary research · 2018Article
- Article
- MyD88 Mediates Instructive Signaling in Dendritic Cells and Protective Inflammatory Response during Rickettsial Infection.Infection and immunity · 2016Article
- The role of CD8 T lymphocytes in rickettsial infections.Seminars in immunopathology · 2015Review
- Stat1 negatively regulates immune-mediated injury with Anaplasma phagocytophilum infection.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Anaplasma phagocytophilum, interferon gamma production and Stat1 signaling.Microbiology and immunology · 2013Article
- Anaplasma phagocytophilum dihydrolipoamide dehydrogenase 1 affects host-derived immunopathology during microbial colonization.Infection and immunity · 2012Article
- Anaplasma phagocytophilum: deceptively simple or simply deceptive?Future microbiology · 2012Review
- Adaptive immunity to Anaplasma pathogens and immune dysregulation: implications for bacterial persistence.Comparative immunology, microbiology and infectious diseases · 2012Review
- The biological basis of severe outcomes in Anaplasma phagocytophilum infection.FEMS immunology and medical microbiology · 2012Review
- Dexamethasone-induced cytokine changes associated with diminished disease severity in horses infected with Anaplasma phagocytophilum.Clinical and vaccine immunology : CVI · 2011Article
- Mitogenic component in polar lipid-enriched Anaplasma phagocytophilum membranes.Clinical and vaccine immunology : CVI · 2007Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
In mice, Anaplasma phagocytophilum control is independent of phagocyte oxidase (phox), inducible NO synthase (NOS2), tumor necrosis factor (TNF), and MyD88 Toll-like receptor signaling. We show that despite evasion of these host responses, phox, NOS2, TNF, and MyD88 are activated and contribute to inflammation and hepatic injury more than A. phagocytophilum itself.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.