ArticleProceedings of the National Academy of Sciences of the United States of America2006
Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 415 papers, 1 of them a synthesis that pooled it.
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Who cites it
415 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,133 citations in OpenAlex.
- Pathogenesis-related protein 10 in resistance to biotic stress: progress in elucidating functions, regulation and modes of action.Frontiers in plant science · 2023Pooled it
- Chitosan activates a sequential CaPlant signaling & behavior · 2026Article
- Longitudinal zone- and cell type-specific pattern-triggered immune responses in Arabidopsis roots.Developmental cell · 2026Article
- A fungal subtilase-like protease SBT1 blocks rice immunity by erasing the MAPKKKα signaling node.Science advances · 2026Article
- Biological Control ofMicroorganisms · 2026Article
- Fusarium sacchari 14-3-3 Protein FsBmh1 Sequesters a Novel Elicitor FsEcm33 to Evade Host Immunity.Molecular plant pathology · 2026Article
- The grapevine LysM receptor kinase VvLYK4-2 is a key player in chitosan-triggered immune responses.Horticulture research · 2026Article
- MoChia1 is a GH18 reducing-end GlcNAc-releasing chitin oligosaccharide hydrolase from the rice blast fungus Magnaporthe oryzae.The Journal of biological chemistry · 2026Article
- Foliar Application of Chitosan Nanoparticles Mitigates Early Physiological and Antioxidant Responses ofPolymers · 2026Article
- Refractory Behavior in Plant Cells-Calcium Signaling Induced by Biotic Stress.Plants (Basel, Switzerland) · 2026Review
- CRISPR/Cas9-based knockout of BnaLYK compromises pattern-triggered immunity and resistance to Sclerotinia sclerotiorum in Brassica napus.BMC plant biology · 2026Article
- Plant cell surface receptors.The Plant journal : for cell and molecular biology · 2026Review
- AtLYK4 is the major chitin receptor in Arabidopsis with N-glycosylation and ligand-interacting residues orchestrating chitin perception.Science China. Life sciences · 2026Article
- Plant cell walls as a key driver of plant-pathogen coevolution.FEMS microbiology reviews · 2026Review
- Comparative RNA sequencing analysis of resistant and susceptible Dendrobium "Earsakul" under black rot challenge.Biotechnologia · 2026Article
- Review
- Grapevine LysM-containing receptor-like kinaseFrontiers in plant science · 2026Article
- A GmNRF5a-GmCERK1-GmCAK1 module mediates chitin/chitosan-triggered immune response in soybean.Journal of integrative plant biology · 2026Article
- LYM2 mediates chitin-induced plasmodesmal flux reduction inFrontiers in plant science · 2026Article
- CtChi19: a valuable gene for improving resistance to Botrytis cinerea and Alternaria alternata in Carthamus tinctorius.Frontiers in plant science · 2026Article
355 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chitin is a major component of fungal cell walls and serves as a molecular pattern for the recognition of potential pathogens in the innate immune systems of both plants and animals. In plants, chitin oligosaccharides have been known to induce various defense responses in a wide range of plant cells including both monocots and dicots. To clarify the molecular machinery involved in the perception and transduction of chitin oligosaccharide elicitor, a high-affinity binding protein for this elicitor was isolated from the plasma membrane of suspension-cultured rice cells. Characterization of the purified protein, CEBiP, as well as the cloning of the corresponding gene revealed that CEBiP is actually a glycoprotein consisting of 328 amino acid residues and glycan chains. CEBiP was predicted to have a short membrane spanning domain at the C terminus. Knockdown of CEBiP gene by RNA interference resulted in the suppression of the elicitor-induced oxidative burst as well as the gene responses, showing that CEBiP plays a key role in the perception and transduction of chitin oligosaccharide elicitor in the rice cells. Structural analysis of CEBiP also indicated the presence of two LysM motifs in the extracellular portion of CEBiP. As the LysM motif has been known to exist in the putative Nod-factor receptor kinases involved in the symbiotic signaling between leguminous plants and rhizobial bacteria, the result indicates the involvement of partially homologous plasma membrane proteins both in defense and symbiotic signaling in plant cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.