Evidence map›Paper›PMID 16825393›Full record

ArticleJournal of clinical microbiology2006

Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens.

Didi Bang, Ase Bengård Andersen, Vibeke Østergaard Thomsen

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. The occurrence and frequency of genomic mutations that mediate Isoniazid and Rifampicin resistance inMalawi medical journal : the journal of Medical Association of Malawi · 2018
    Article
  4. Article
  5. Article
  6. Pulmonary Tuberculosis Diagnosis: Where We Are?Tuberculosis and respiratory diseases · 2016
    Review
  7. General and advanced diagnostic tools to detect Mycobacterium tuberculosis and their drug susceptibility: a review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Multidrug-resistant tuberculosis: rapid detection of resistance to rifampin and high or low levels of isoniazid in clinical specimens and isolates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2008
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Didi BangDidi Bang, International Reference Laboratory of Mycobacteriology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark. DVB@ssi.dk
Ase Bengård Andersen
Vibeke Østergaard Thomsen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A multiplex PCR DNA strip assay (Genotype MTBDR) designed to detect rifampin (rpoB) and high-level isoniazid (katG) resistance mutations in Mycobacterium tuberculosis isolates was optimized for clinical specimens. Successful genotypic results were achieved with 36 of 38 (95%) smear-positive respiratory specimens, allowing rapid therapeutic adjustments in transmittable drug-resistant tuberculosis.

Indexed as

Antibiotics, AntitubercularAntitubercular AgentsBody FluidsDrug Resistance, BacterialGenotypeHumansIsoniazidMicrobial Sensitivity TestsMycobacterium tuberculosisPolymerase Chain ReactionRifampinTuberculosis, Multidrug-ResistantAntibiotics, AntitubercularAntitubercular AgentsIsoniazidRifampin

Identifiers

PMID16825393
PMCPMC1489488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.