ArticleJournal of clinical microbiology2006
Molecular epidemiologic identification of Escherichia coli genes that are potentially involved in movement of the organism from the intestinal tract to the vagina and bladder.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Characterization of broad-host-range bacteriophages targeting multidrug-resistant E. coli and Shigella spp.: in vitro potential.BMC microbiology · 2026Article
- Hypo-osmotic stress is an anticipatory trigger of heat-resistance in presumptive extraintestinal pathogenicFrontiers in microbiology · 2025Article
- Investigation of the biofilm formation in extra-intestinal pathogenic Escherichia coli ST131 strains and its correlation with the presence of fimH, afa, and kpsMSTII genes.Journal of applied genetics · 2023Article
- Virulence Profile, Antibiotic Resistance, and Phylogenetic Relationships amongPathogens (Basel, Switzerland) · 2022Article
- Effects of a 10-Strain Oral Probiotic on Parameters of Vaginal Health and Microbial Community: A Pilot Clinical Study.International journal of women's health · 2022Article
- Article
- Nonantibiotic prevention and management of recurrent urinary tract infection.Nature reviews. Urology · 2018Review
- Genotypic Characterization of Virulence Factors inJournal of clinical and diagnostic research : JCDR · 2016Article
- Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges.Clinical microbiology reviews · 2014Review
- Efficient and cost-effective alternative treatment for recurrent urinary tract infections and interstitial cystitis in women: a two-case report.Case reports in medicine · 2014Article
- Alternative approaches to conventional treatment of acute uncomplicated urinary tract infection in women.Current infectious disease reports · 2013Article
- Fimbrial profiles predict virulence of uropathogenic Escherichia coli strains: contribution of ygi and yad fimbriae.Infection and immunity · 2011Article
- Abnormal immunological profile and vaginal microbiota in women prone to urinary tract infections.Clinical and vaccine immunology : CVI · 2009Article
- ZapA, a virulence factor in a rat model of Proteus mirabilis-induced acute and chronic prostatitis.Infection and immunity · 2008Article
- Transcriptomics and adaptive genomics of the asymptomatic bacteriuria Escherichia coli strain 83972.Molecular genetics and genomics : MGG · 2008Article
- Probe hybridization array typing: a binary typing method for Escherichia coli.Journal of clinical microbiology · 2007Article
- Identification of new genetic regions more prevalent in nontypeable Haemophilus influenzae otitis media strains than in throat strains.Journal of clinical microbiology · 2006Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A first step in urinary tract infection (UTI) pathogenesis in the otherwise healthy host is the movement of uropathogenic Escherichia coli from the intestinal tract to the urinary tract. We conducted a genomic subtraction to isolate genetic regions associated with this movement. A representative UTI isolate present in the rectum, vagina, and bladder of a woman with UTI was chosen as the tester; the driver was a phylogenetically distant rectal isolate (based on pulsed-field gel electrophoresis analysis) with a profile of uropathogenic virulence genes similar to that of the tester. Tester-specific regions identified by the subtraction were screened, using DNA dot blot hybridization, against a collection of 88 uropathogens isolated from the rectum, urine, and/or vagina of women with UTIs and 54 E. coli isolates from the same women that were found only in the rectum. Twelve genetic regions occurred more often in multisite isolates than in rectal site-only isolates. Eleven of these 12 genetic regions are homologous to regions in the sequenced uropathogenic E. coli CFT073 strain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.