ArticleJournal of exposure science & environmental epidemiology2007
Living in a sea of lead--changes in blood- and hand-lead of infants living near a smelter.
Article in Journal of exposure science & environmental epidemiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Correlation between lead speciation and inhalation bioaccessibility using two different simulated lung fluids.Environmental pollution (Barking, Essex : 1987) · 2020Article
- Dynamics of Lead Bioavailability and Speciation in Indoor Dust and X-ray Spectroscopic Investigation of the Link between Ingestion and Inhalation Pathways.Environmental science & technology · 2019Article
- Locally produced chicken eggs-a source of dietary lead for an Australian community living with an active lead smelter?Journal of exposure science & environmental epidemiology · 2019Article
- Comments on manuscript--Zheng, J., Huynh, T., Gasparon, M., Ng, J. and Noller, B., 2013. Human health risk assessment of lead from mining activities at semi-arid locations in the context of total lead exposure. Environmental Science and Pollution Research, 20, 8404-8416.Environmental science and pollution research international · 2015Article
- Size-resolved dust and aerosol contaminants associated with copper and lead smelting emissions: implications for emission management and human health.The Science of the total environment · 2014Article
- Ethical issues in using children's blood lead levels as a remedial action objective.American journal of public health · 2011Article
- Disproportionate exposures in environmental justice and other populations: the importance of outliers.American journal of public health · 2011Review
- Arsenic distribution and bioaccessibility across particle fractions in historically contaminated soils.Environmental geochemistry and health · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirteen infants born into the lead contaminated environment of Port Pirie, South Australia, were followed approximately monthly from birth until they were about 36 months. Blood-lead levels of infants at birth were similar to their mothers but fell rapidly during the first 35 days of life. Thereafter, infants born with blood-lead levels at about 2-4 microg/dl began a slow linear increase until 14-18 months where a plateau occurred of 10.8-17.2 microg/dl. The blood-lead levels were well correlated with hand-lead loadings of infant (r(2)=0.72, P<0.01, log transformed data) and mother (r(2)=0.62, P<0.01, log transformed data) unless the birth lead level was exceptionally high. The principle factor determining exposure was the impact of smelter emissions on the house. Blood-lead increase was caused by the relatively more rapid increase in dose of lead compared with the increasing body mass, which was related directly to the maturation of motor development. Hand-lead of mothers were closely related to both infants' blood- and hand-lead levels until the point of blood-lead plateau then substantially fell as infants began to walk unaided. The estimated slope factor using the ICRP model was 0.75-0.94 microg/dl per microg/day with a maximum daily dose of 3-5 microg/kg/day, assuming 45% absorption. Ingestion appears to be the most likely route for at least 95% of the dose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.