Evidence map›Paper›PMID 16822395›Full record

ReviewCurrent atherosclerosis reports2006

Management of symptomatic intracranial arterial stenosis: endovascular therapy.

Mikael Mazighi, Alex Abou-Chebl

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mikael MazighiDepartment of Neurology, S 90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. mazighm@ccf.org
Alex Abou-Chebl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with symptomatic intracranial stenosis are at high risk of subsequent stroke despite the use of antithrombotic agents or surgical management. Although endovascular therapy appears to promise therapeutic solutions, the reported high peri-procedural adverse event rate limits the widespread use of this technique. In the past few years, the morbidity and mortality associated with intracranial angioplasty and stenting have decreased with the development of new intracranial specific devices. The most recent prospective studies on intracranial stenting have been nothing more than registries of patients with symptomatic intracranial stenosis of 50% or greater who have failed medical therapy. However, no randomized controlled data exist on the comparison between endovascular therapy and medical treatment. There are new data identifying factors associated with a higher risk of stroke in medically treated patients. These findings will help to define a high-risk patient population on whom the initial controlled trials will be conducted.

Indexed as

Constriction, PathologicHumansIntracranial Arterial DiseasesStentsTreatment OutcomeVascular Surgical Procedures

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.