Evidence map›Paper›PMID 16822394›Full record

ReviewCurrent atherosclerosis reports2006

Symptomatic and asymptomatic carotid stenosis: how, when, and who to treat?

Peter M Rothwell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Perimetric and retrobulbar blood flow changes following carotid endarterectomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter M RothwellStroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, United Kingdom. peter.rothwell@clneuro.ox.ac.uk
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotid stenosis is an important cause of ischemic stroke. Large randomized trials of endarterectomy have shown that surgery reduces the risk of stroke in patients with recently symptomatic carotid stenosis of 50% or greater, and to a lesser extent in patients with asymptomatic carotid stenosis of 60% or greater. More recent research has gone some way in identifying which patients benefit most and when intervention is most effective. Individual risk modeling has been shown to be useful in selecting patients with the most to gain from endarterectomy for symptomatic stenosis, although timely surgery and optimal medical treatment are of equal importance. Further research is required in order to determine the role of carotid stenting and to identify those individuals with asymptomatic stenosis who have the most to gain from intervention.

Indexed as

Carotid StenosisDecision Support TechniquesEndarterectomy, CarotidHumansPractice Patterns, Physicians'

Identifiers

PMID16822394
OpenAlexW2029882644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.