ReviewGene therapy2006
Gene therapy progress and prospects: cystic fibrosis.
Review in Gene therapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Four decades of adenovirus gene transfer vectors: History and current use.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- The Impact of Nano-Hydroxyapatite Scaffold Enrichment on Bone Regeneration In Vivo-A Systematic Review.Biomimetics (Basel, Switzerland) · 2024Review
- Barriers to inhaled gene therapy of obstructive lung diseases: A review.Journal of controlled release : official journal of the Controlled Release Society · 2016Review
- Redesign of extensive protein-DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway.Gene therapy · 2014Article
- A synthetic chloride channel restores chloride conductance in human cystic fibrosis epithelial cells.PloS one · 2012Article
- Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients.PloS one · 2011Article
- Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length.Respiratory research · 2010Article
- Toward gene therapy for cystic fibrosis using a lentivirus pseudotyped with Sendai virus envelopes.Molecular therapy : the journal of the American Society of Gene Therapy · 2010Article
- Targeted delivery of nucleic-acid-based therapeutics to the pulmonary circulation.The AAPS journal · 2009Review
- Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.Human gene therapy · 2009Article
- Extracellular barriers in respiratory gene therapy.Advanced drug delivery reviews · 2009Review
- Progress and prospects: the design and production of plasmid vectors.Gene therapy · 2009Review
- What's new in cystic fibrosis? From treating symptoms to correction of the basic defect.European journal of pediatrics · 2008Review
- Bactofection of lung epithelial cells in vitro and in vivo using a genetically modified Escherichia coli.Gene therapy · 2008Article
- Impact of deletion of envelope-related genes of recombinant Sendai viruses on immune responses following pulmonary gene transfer of neonatal mice.Gene therapy · 2007Article
- Cystic fibrosis transmembrane regulator protein mutations: 'class' opportunity for novel drug innovation.Paediatric drugs · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our first review on progress and prospects in cystic fibrosis (CF) gene therapy was published in this series in October 2002. We now summarize the progress made since then and comment on the prospects for CF gene therapy over the next couple of years. Three clinical trials have been carried out, further supporting the proof-of-principle that gene transfer to the airway epithelium is feasible. Developments in viral and non-viral vectors, as well as recent alternative strategies such as gene repair, trans-splicing and stem cell therapy will be reviewed.
Indexed as
Identifiers
16819538What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.