A simple principle to explain the evolution of pre-mRNA splicing.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. OpenASO: RNA Rescue-designing splice-modulating antisense oligonucleotides through community science.RNA (New York, N.Y.) · 2025
   Article
2. Self-empowerment of life through RNA networks, cells and viruses.F1000Research · 2023
   Review
3. Single nucleotide polymorphism (SNP) in theWellcome open research · 2022
   Article
4. Stress-mediated convergence of splicing landscapes in male and female rock doves.BMC genomics · 2020
   Article
5. Genome-wide evolution of wobble base-pairing nucleotides of branchpoint motifs with increasing organismal complexity.RNA biology · 2020
   Article
6. Targeting Splicing in the Treatment of Human Disease.Genes · 2017
   Review
7. Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo.RNA (New York, N.Y.) · 2015
   Article
8. ProbeAlign: incorporating high-throughput sequencing-based structure probing information into ncRNA homology search.BMC bioinformatics · 2014
   Article
9. Comparative analysis of information contents relevant to recognition of introns in many species.BMC genomics · 2011
   Article
10. Fas splicing regulation during early apoptosis is linked to caspase-mediated cleavage of U2AF65.Molecular biology of the cell · 2008
    Article
11. Width of gene expression profile drives alternative splicing.PloS one · 2008
    Article
12. Large-scale comparative analysis of splicing signals and their corresponding splicing factors in eukaryotes.Genome research · 2008
    Article
13. Coevolutionary networks of splicing cis-regulatory elements.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article

Corrections and comments

• Comment on
  RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.2006

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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