ReviewOrphanet journal of rare diseases2006
Hypersensitivity pneumonitis.
Review in Orphanet journal of rare diseases, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Diagnosis and Treatment of Hypersensitivity Pneumonitis: S2k Guideline of the German Respiratory Society and the German Society for Allergology and Clinical Immunology.Respiration; international review of thoracic diseases · 2025Guideline
- Two Blood-based Endotypes Reveal Divergent Clinical Outcomes of Fibrotic Hypersensitivity Pneumonitis.medRxiv : the preprint server for health sciences · 2026Article
- Sex-specific aspects in a population of patients undergoing evaluation for interstitial lung disease with transbronchial cryobiopsy.Scientific reports · 2025Article
- A Case of Immunomodulator-Responsive Hypersensitivity Pneumonitis Secondary to Chronic Passive Smoke Inhalation.Cureus · 2024Article
- Hypersensitivity Pneumonia Due to Lentil Aspiration: A Rare but Painstaking Pulmonary Illness.Global pediatric health · 2024Article
- Recurrent episodes of febrile dyspnoea: hypersensitivity pneumonitis caused by a household ultrasonic humidifier.BMJ case reports · 2023Article
- Functional Clustering of Metabolically Related Genes Is Conserved acrossJournal of fungi (Basel, Switzerland) · 2023Review
- Occupational hypersensitivity pneumonia.Tuberkuloz ve toraks · 2023Review
- Sooty bark disease of maples: the risk for hypersensitivity pneumonitis by fungal spores not only for woodman.Journal of occupational medicine and toxicology (London, England) · 2021Review
- Bronchoalveolar lavage as a diagnostic procedure: a review of known cellular and molecular findings in various lung diseases.Journal of thoracic disease · 2020Review
- Zoonotic diseases from birds to humans in Vietnam: possible diseases and their associated risk factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- NK and NKT cells in the diagnosis of diffuse lung diseases presenting with a lymphocytic alveolitis.BMC pulmonary medicine · 2019Article
- Outcomes of immunosuppressive therapy in chronic hypersensitivity pneumonitis.ERJ open research · 2017Article
- Hypersensitivity pneumonitis: an overlooked cause of cough and dyspnea.Journal of community hospital internal medicine perspectives · 2017Article
- A Case of Chronic Cough in a Winemaker.Respiratory medicine case reports · 2017Article
- Hypersensitivity pneumonitis: a complex lung disease.Clinical and molecular allergy : CMA · 2017Review
- Imaging of Hypersensitivity Pneumonitis.Radiologic clinics of North America · 2016Review
- The Role and Immunobiology of Eosinophils in the Respiratory System: a Comprehensive Review.Clinical reviews in allergy & immunology · 2016Review
- Chronic hypersensitivity pneumonitis.Journal of asthma and allergy · 2016Review
- Spotlight on the diagnosis of extrinsic allergic alveolitis (hypersensitivity pneumonitis).Journal of occupational medicine and toxicology (London, England) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypersensitivity pneumonitis (HP) is a pulmonary disease with symptoms of dyspnea and cough resulting from the inhalation of an antigen to which the subject has been previously sensitized. The incidence of HP is unknown. A population-based study estimated the annual incidence of interstitial lung diseases as 30:100,000 and HP accounted for less than 2% of these cases. The diagnosis of HP can often be made or rejected with confidence, especially in areas of high or low prevalence respectively, using simple diagnostic criteria. Chest X-rays may be normal in active HP; High Resolution Computed Tomography is sensitive but not specific for the diagnosis of HP. The primary use of pulmonary function tests is to determine the physiologic abnormalities and the associated impairment. Despite the pitfalls of false positive and false negatives, antigen-specific IgG antibodies analysis can be useful as supportive evidence for HP. Bronchoalveolar lavage plays an important role in the investigation of patients suspected of having HP. A normal number of lymphocytes rules out all but residual disease. Surgical lung biopsy should be reserved for rare cases with puzzling clinical presentation or for verification the clinical diagnosis when the clinical course or response to therapy is unusual. Being an immune reaction in the lung, the most obvious treatment of HP is avoidance of contact with the offending antigen. Systemic corticosteroids represent the only reliable pharmacologic treatment of HP but do not alter the long-term outcome. The use of inhaled steroids is anecdotal. Treatment of chronic or residual disease is supportive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.