ArticleEuropean archives of psychiatry and clinical neuroscience2006
Taenia solium DNA is present in the cerebrospinal fluid of neurocysticercosis patients and can be used for diagnosis.
Article in European archives of psychiatry and clinical neuroscience, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 74 citations in OpenAlex.
- A systematic review of selected food-borne helminthiases in Southeast Asia with emphasis on anthelminthic treatment regimens.Food and waterborne parasitology · 2026Article
- Taenia solium neurocysticercosis: Its current epidemiological, diagnostic, therapeutic, and control landscapes.PLoS neglected tropical diseases · 2026Review
- Molecular diagnostics in cerebrospinal fluid for the diagnosis of central nervous system infections.Clinical microbiology reviews · 2024Review
- From laboratory to clinical practice: an update of the immunological and molecular tools for neurocysticercosis diagnosis.Frontiers in parasitology · 2024Review
- Serological and molecular detection of neurocysticercosis among epileptic patients in Nagpur, Maharashtra state (India).Helminthologia · 2023Article
- Cell-free DNA-based liquid biopsies in neurology.Brain : a journal of neurology · 2023Review
- Update on the diagnosis and management of neurocysticercosis.Arquivos de neuro-psiquiatria · 2022Review
- Selection of new diagnostic markers for Dirofilaria repens infections with the use of phage display technology.Scientific reports · 2022Article
- Collaborative Studies for the Detection ofMicroorganisms · 2021Article
- Neurocysticercosis Diagnosed byCase reports in infectious diseases · 2020Article
- Detection ofThe American journal of tropical medicine and hygiene · 2019Article
- Comparison of complementary diagnostic tests in cerebrospinal fluid and serum for neurocysticercosis.Heliyon · 2018Article
- Next generation sequencing based pathogen analysis in a patient with neurocysticercosis: a case report.BMC infectious diseases · 2018Article
- Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Neurocysticercosis.Frontiers in neurology · 2018Article
- Present status of laboratory diagnosis of human taeniosis/cysticercosis in Europe.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Review
- Validity of a PCR assay in CSF for the diagnosis of neurocysticercosis.Neurology(R) neuroimmunology & neuroinflammation · 2017Article
- Application of polymerase chain reaction on cerebrospinal fluid for diagnosis of cerebral coenurosis in small ruminants.Parasitology research · 2015Article
- Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis.Journal of neuroinflammation · 2014Article
- Molecular testing for clinical diagnosis and epidemiological investigations of intestinal parasitic infections.Clinical microbiology reviews · 2014Review
- Overview of the effect and epidemiology of parasitic central nervous system infections in African children.Seminars in pediatric neurology · 2014Review
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurocysticercosis is the most frequent parasitic infection of the CNS and the main cause of acquired epilepsy worldwide. Seizures are the most common symptoms of the disease, together with headache, involuntary movements, psychosis and a global mental deterioration. Absolute diagnostic criteria include the identification of cysticerci, with scolex, in the brain by MRI imaging. We demonstrate here, for the first time, that T. solium DNA is present in the cerebrospinal fluid of patients. The PCR amplification of the parasite DNA in the CSF enabled the correct identification of 29/30 cases (96.7 %). The PCR diagnosis of parasite DNA in the CSF may be a strong support for the diagnosis of neurocysticercosis.
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