ArticleJournal of bacteriology2006
Limited role for the DsrA and RprA regulatory RNAs in rpoS regulation in Salmonella enterica.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- From Environmental Persistence to Host Adaptation: Differential Curli Regulation inMicroorganisms · 2026Review
- Advances in sRNA-mediated regulation ofFrontiers in cellular and infection microbiology · 2025Review
- sRNA molecules participate in hyperosmotic stress response regulation inApplied and environmental microbiology · 2024Article
- TusA Is a Versatile Protein That Links Translation Efficiency to Cell Division in Escherichia coli.Journal of bacteriology · 2021Article
- Small RNA-based feedforward loop with AND-gate logic regulates extrachromosomal DNA transfer in Salmonella.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium.Nucleic acids research · 2013Article
- A novel insight on signal transduction mechanism of RcsCDB system in Salmonella enterica serovar typhimurium.PloS one · 2013Article
- Hfq-dependent, co-ordinate control of cyclic diguanylate synthesis and catabolism in the plague pathogen Yersinia pestis.Molecular microbiology · 2012Article
- sRNAs and the virulence of Salmonella enterica serovar Typhimurium.RNA biology · 2012Review
- Effect of salt and RNA structure on annealing and strand displacement by Hfq.Nucleic acids research · 2009Article
- Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq.PLoS genetics · 2008Article
- Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5'-leader.RNA (New York, N.Y.) · 2008Article
- The RNA chaperone Hfq is essential for the virulence of Salmonella typhimurium.Molecular microbiology · 2007Article
- Characterization of the role of ribonucleases in Salmonella small RNA decay.Nucleic acids research · 2007Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
RpoS, the sigma factor of enteric bacteria that responds to stress and stationary phase, is subject to complex regulation acting at multiple levels, including transcription, translation, and proteolysis. Increased translation of rpoS mRNA during growth at low temperature, after osmotic challenge, or with a constitutively activated Rcs phosphorelay depends on two trans-acting small regulatory RNAs (sRNAs) in Escherichia coli. The DsrA and RprA sRNAs are both highly conserved in Salmonella enterica, as is their target, an inhibitory antisense element within the rpoS untranslated leader. Analysis of dsrA and rprA deletion mutants indicates that while the increased translation of RpoS in response to osmotic challenge is conserved in S. enterica, dependence on these two sRNA regulators is much reduced. Furthermore, low-temperature growth or constitutive RcsC activation had only modest effects on RpoS expression, and these increases were, respectively, independent of dsrA or rprA function. This lack of conservation of sRNA function suggests surprising flexibility in RpoS regulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.