ReviewNeuroRx : the journal of the American Society for Experimental NeuroTherapeutics2006
Redox proteomics in some age-related neurodegenerative disorders or models thereof.
Review in NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- Alzheimer's disease is an inherent, natural part of human brain aging: an integrated perspective.Free neuropathology · 2022Article
- Grape Seed Proanthocyanidin and Swimming Exercise Protects Against Cognitive Decline: A Study on M1 Acetylcholine Receptors in Aging Male Rat Brain.Neurochemical research · 2017Article
- Improving effect of chronic resveratrol treatment on central monoamine synthesis and cognition in aged rats.Age (Dordrecht, Netherlands) · 2015Article
- Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases.Immunity & ageing : I & A · 2015Review
- Age-related learning and memory deficits in rats: role of altered brain neurotransmitters, acetylcholinesterase activity and changes in antioxidant defense system.Age (Dordrecht, Netherlands) · 2014Article
- Evaluation of Safety and Protective Effect of Combined Extract of Cissampelos pareira and Anethum graveolens (PM52) against Age-Related Cognitive Impairment.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.Brain pathology (Zurich, Switzerland) · 2010Review
- Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis.Acta neuropathologica · 2009Review
- Lipid peroxidation scavengers prevent the carbonylation of cytoskeletal brain proteins induced by glutathione depletion.Neurochemical research · 2007Article
- Age-related subproteomic analysis of mouse liver and kidney peroxisomes.Proteome science · 2007Article
- Two-dimensional protein electrophoresis: from molecular pathway discovery to biomarker discovery in neurological disorders.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2006Review
- Liquid chromatography with tandem mass spectrometry-based proteomic discovery in aging and Alzheimer's disease.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2006Review
- Homogenous and Microbeam X-Ray Radiation Induces Proteomic Changes in the Brains of Irradiated Rats and in the Brains of Nonirradiated Cage Mate Rats.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Neurodegenerative diseases cause memory loss and cognitive impairment. Results from basic and clinical scientific research suggest a complex network of mechanisms involved in the process of neurodegeneration. Progress in treatment of such disorders requires researchers to better understand the functions of proteins involved in neurodegenerative diseases, to characterize their role in pathogenic disease mechanisms, and to explore their roles in the diagnosis, treatment, and prevention of neurodegenerative diseases. A variety of conditions of neurodegenerative diseases often lead to post-translational modifications of proteins, including oxidation and nitration, which might be involved in the pathogenesis of neurodegenerative diseases. Redox proteomics, a subset of proteomics, has made possible the identification of specifically oxidized proteins in neurodegenerative disorders, providing insight into a multitude of pathways that govern behavior and cognition and the response of the nervous system to injury and disease. Proteomic analyses are particularly suitable to elucidate post-translational modifications, expression levels, and protein-protein interactions of thousands of proteins at a time. Complementing the valuable information generated through the integrative knowledge of protein expression and function should enable the development of more efficient diagnostic tools and therapeutic modalities. Here we review redox proteomic studies of some neurodegenerative diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.