Evidence map›Paper›PMID 16815030›Full record

ReviewTrends in endocrinology and metabolism: TEM2006

Membrane guanylyl cyclase receptors: an update.

David L Garbers, Ted D Chrisman, Phi Wiegn, Takeshi Katafuchi, Joseph P Albanesi, Vincent Bielinski, Barbara Barylko, Margaret M Redfield, John C Burnett

Open access · greenAbstract readReview
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Adenylate Cyclases ofPathogens (Basel, Switzerland) · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Novel vasodilators in heart failure.Current heart failure reports · 2013
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

David L GarbersCecil H. & Ida Green Center for Reproductive Biology Sciences, and Department of Pharmacology, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390-9051, USA. david.garbers@utsouthwestern.edu
Ted D Chrisman
Phi Wiegn
Takeshi Katafuchi
Joseph P Albanesi
Vincent Bielinski
Barbara Barylko
Margaret M Redfield
John C Burnett
Howard Hughes Medical Institute · USThe University of Texas Southwestern Medical Center · USMayo Clinic · USSouthwestern Medical Center · US

Funding

INTRARENAL REGULATION OF SODIUM EXCRETIONR01HL036634 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C · 1987 to 2019
$6.5M
Guanylyl cyclase receptors: Targets for medical interventionR01DK073120 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI ALBANESI, JOSEPH P · 2006 to 2010
$1.7M
MECHANISMS OF RENAL IMPAIRMENT IN HYPERCHOLESTEROLEMIAR01HL063282 · NHLBI · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI LERMAN, LILACH O · 2000 to 2003
$847k
NHLBI NIH HHS HL 36634NHLBI NIH HHS HL 63282NHLBI NIH HHS HL 776611NHLBI NIH HHS R01 HL036634NHLBI NIH HHS R01 HL063282NIDDK NIH HHS DK 73120NIDDK NIH HHS R01 DK073120
6 · The paper itself

Abstract

Recent studies have demonstrated key roles for several membrane guanylyl cyclase receptors in the regulation of cell hyperplasia, hypertrophy, migration and extracellular matrix production, all of which having an impact on clinically relevant diseases, including tissue remodeling after injury. Additionally, cell differentiation, and even tumor progression, can be profoundly influenced by one or more of these receptors. Some of these receptors also mediate important communication between the heart and intestine, and the kidney to regulate blood volume and Na+ balance.

Indexed as

AnimalsAtrial Natriuretic FactorGuanylate CyclaseHumansIntestinesLysophospholipidsModels, BiologicalNatriuretic Peptide, BrainNatriuretic Peptide, C-TypeNatriuretic PeptidesOsteogenesisReceptors, Atrial Natriuretic FactorReceptors, Guanylate Cyclase-CoupledSignal TransductionSphingosineAtrial Natriuretic Factoratrial natriuretic factor receptor AGuanylate CyclaseLysophospholipidsNatriuretic Peptide, BrainNatriuretic Peptide, C-TypeNatriuretic PeptidesReceptors, Atrial Natriuretic FactorReceptors, Guanylate Cyclase-CoupledSphingosinesphingosine 1-phosphate

Identifiers

PMID16815030
PMCPMC2647281
OpenAlexW1976200721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.