ArticleWorld journal of gastroenterology2006
In vitro screening of traditionally used medicinal plants in China against enteroviruses.
Article in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Isolation of Two Antiviral Compounds from Pelargonium Graveolens Displaying Different Modes of Action.Current microbiology · 2025Article
- Screening compounds for treating the diabetes and COVID-19 from Miao medicine by molecular docking and bioinformatics.Arabian journal of chemistry · 2023Article
- A Review of the Pharmacological Potential ofCells · 2022Review
- Broad-spectrum antiviral activity of Spatholobus suberectus Dunn against SARS-CoV-2, SARS-CoV-1, H5N1, and other enveloped viruses.Phytotherapy research : PTR · 2022Article
- In vitro protective effects of Paeonia mascula subsp. hellenica callus extract on human keratinocytes.Scientific reports · 2020Article
- A Review of theMolecules (Basel, Switzerland) · 2020Review
- Large-Scale Screening of 239 Traditional Chinese Medicinal Plant Extracts for Their Antibacterial Activities against Multidrug-ResistantPathogens (Basel, Switzerland) · 2020Article
- Screen for Potential Candidate Alternatives ofInternational journal of molecular sciences · 2019Article
- Isolation of Strong Antioxidants fromAntioxidants (Basel, Switzerland) · 2019Article
- Reversal of Multidrug Resistance in Human Colon Cancer and Human Leukemia Cells by Three Plant Extracts and Their Major Secondary Metabolites.Medicines (Basel, Switzerland) · 2018Article
- In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn.Molecules (Basel, Switzerland) · 2016Article
- Simultaneous Determination of Four Active Ingredients in Sargentodoxa cuneata by HPLC Coupled with Evaporative Light Scattering Detection.International journal of analytical chemistry · 2016Article
- Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin.BioMed research international · 2015Article
- Article
- MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells.Virology journal · 2014Article
- Activation of JNK1/2 and p38 MAPK signaling pathways promotes enterovirus 71 infection in immature dendritic cells.BMC microbiology · 2014Article
- Inhibitory effects of Cyrtomium fortunei J. Smith root extract on melanogenesis.Pharmacognosy magazine · 2013Article
- A survey of chinese medicinal herbal treatment for chemotherapy-induced oral mucositis.Evidence-based complementary and alternative medicine : eCAM · 2013Review
- Enterovirus infection in Korean children and anti-enteroviral potential candidate agents.Korean journal of pediatrics · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo search for new antiviral agents from traditional Chinese medicine, specifically anti-enteroviruses agents.
methodsThe aqueous extracts (AE) of more than 100 traditionally used medicinal plants in China were evaluated for their in vitro anti-Coxsackie virus B3 activities with a MTT-based colorimetric assay.
resultsThe test for AE of 16 plants exhibited anti-Coxsackie virus B3 activities at different magnitudes of potency. They can inhibit three steps (inactivation, adsorption and replication) during the infection. Among the 16 plants, Sargentodoxa cuneata (Oliv.) Rehd. et Wils., Sophora tonkinensis Gapnep., Paeonia veitchii Lynch, Spatholobus suberectus Dunn. and Cyrtomium fortunei J. sm. also have activity against other enterovirus, including Coxsackie virus B5, Polio virus I, Echo virus 9 and Echo virus 29. Cell cytotoxic assay demonstrated that all tested AE had CC50 values higher than their EC50 values.
conclusionThe sixteen traditionally used medicinal plants in China possessed antiviral activity, and some of them merit further investigations.
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