ArticleJournal of the American Society for Mass Spectrometry2006
MALDI analysis of oligonucleotides directly from montmorillonite.
Article in Journal of the American Society for Mass Spectrometry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- 6-Aza-2-Thiothymine as an Alternative Matrix for Spatial Proteomics with MALDI-MSI.International journal of molecular sciences · 2024Article
- Mineral-Mediated Oligoribonucleotide Condensation: Broadening the Scope of Prebiotic Possibilities on the Early Earth.Life (Basel, Switzerland) · 2023Article
- Detection of Circulating Serum microRNA/Protein Complexes in ASD Using Functionalized Chips for an Atomic Force Microscope.Molecules (Basel, Switzerland) · 2021Article
- Formation of Abasic Oligomers in Nonenzymatic Polymerization of Canonical Nucleotides.Life (Basel, Switzerland) · 2019Article
- Antireflection Surfaces for Biological Analysis Using Laser Desorption Ionization Mass Spectrometry.Research (Washington, D.C.) · 2018Article
- The Comparison of Hydrochloric Acid and Phosphoric Acid Treatments in the Preparation of Montmorillonite Catalysts for RNA Synthesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Nucleotide Selectivity in Abiotic RNA Polymerization Reactions.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Potential pitfalls in MALDI-TOF MS analysis of abiotically synthesized RNA oligonucleotides.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013Article
- Homochiral selectivity in RNA synthesis: montmorillonite-catalyzed quaternary reactions of D, L-purine with D, L- pyrimidine nucleotides.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2011Article
- Influence of montmorillonite on nucleotide oligomerization reactions: a molecular dynamics study.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2010Article
- MALDI-TOF-MS analysis of small molecules using modified mesoporous material SBA-15 as assisted matrix.Journal of the American Society for Mass Spectrometry · 2009Article
- On the origin of life in the zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on Earth.Biology direct · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oligonucleotides synthesized on a montmorillonite catalyst were analyzed directly. By mixing the catalyst with a matrix (2,4,6-trihydroxyacetophenone or 6-aza-2-thiothymine) and dibasic ammonium citrate, higher molecular weight products were detected compared with "classical" methods such as gel electrophoresis and HPLC with UV as a detector. The oligomers (30-mers and higher) were detected by mass spectrometry even though their concentration was less than 10(-4)% of the total content of the RNA. This method is different from the (MALDI) analysis of the eluates from montmorillonite, which otherwise requires desalting. Placing reaction mixtures with a high concentration of buffers on homoionic, preferably Li-containing, montmorillonite does not require desalting.
Indexed as
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16809045What OpenQuestion holds
Registered trials
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