Evidence map›Paper›PMID 16808776›Full record

Trial reportJournal of general internal medicine2006

Factors associated with the hospitalization of low-risk patients with community-acquired pneumonia in a cluster-randomized trial.

Jose Labarere, Roslyn A Stone, D Scott Obrosky, Donald M Yealy, Thomas P Meehan, Thomas E Auble, Jonathan M Fine, Louis G Graff, Michael J Fine

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guidelines for the management of adult lower respiratory tract infections--full version.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2011
    Guideline
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Community-acquired pneumonia: similarities and differences between European and American guidelines - A narrative review.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The value of prognostic indices for pneumonia.Current infectious disease reports · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jose LabarereVA Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA. Michael.Fine@med.va.gov
Roslyn A Stone
D Scott Obrosky
Donald M Yealy
Thomas P Meehan
Thomas E Auble
Jonathan M Fine
Louis G Graff
Michael J Fine

Funding

RESEARCH PROGRAM TO IMPROVE QUALITY CARE FOR PNEUMONIAK24AI001769 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINE, MICHAEL J · 2000 to 2004
$598k
GUIDELINE TO IMPROVE QUALITY OF INITIAL PNEUMONIA CARER01HS010049 · AHRQ · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINE, MICHAEL J · 1999 to 2002
–
AHRQ HHS R01 HS010049AHRQ HHS R01 HS10049NIAID NIH HHS 5K24 AI01769NIAID NIH HHS K24 AI001769
6 · The paper itself

Abstract

backgroundMany low-risk patients with pneumonia are hospitalized despite recommendations to treat such patients in the outpatient setting.

objectiveTo identify the factors associated with the hospitalization of low-risk patients with pneumonia.

methodsWe analyzed data collected by retrospective chart review for 1,889 low-risk patients (Pneumonia Severity Index [PSI] risk classes I to III without evidence of arterial oxygen desaturation) enrolled in a cluster-randomized trial conducted in 32 emergency departments.

resultsOverall, 845 (44.7%) of all low-risk patients were treated as inpatients. Factors independently associated with an increased odds of hospitalization included PSI risk classes II and III, the presence of medical or psychosocial contraindications to outpatient treatment, comorbid conditions that were not contained in the PSI (cognitive impairment, history of coronary artery disease, diabetes mellitus, or pulmonary disease), multilobar radiographic infiltrates, and home therapy with oxygen, corticosteroids, or antibiotics before presentation. While 32.8% of low-risk inpatients had a contraindication to outpatient treatment and 47.1% had one or more preexisting treatments, comorbid conditions, or radiographic abnormalities not contained in the PSI, 20.1% had no identifiable risk factors for hospitalization other than PSI risk class II or III.

conclusionsHospital admission appears justified for one-third of low-risk inpatients based upon the presence of one or more contraindications to outpatient treatment. At least one-fifth of low-risk inpatients did not have a contraindication to outpatient treatment or an identifiable risk factor for hospitalization, suggesting that treatment of a larger proportion of such low-risk patients in the outpatient setting could be achieved without adversely affecting patient outcomes.

Indexed as

Cluster AnalysisCommunity-Acquired InfectionsHospitalizationHumansInpatientsOdds RatioOutpatientsPneumoniaRetrospective StudiesRisk Assessment

Identifiers

PMID16808776
PMCPMC1924717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.