Evidence map›Paper›PMID 16807780›Full record

ReviewJournal of neuro-oncology2006

Medical management of patients with brain tumors.

Patrick Y Wen, David Schiff, Santosh Kesari, Jan Drappatz, Debra C Gigas, Lisa Doherty

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 189 citations in OpenAlex.

  1. Pooled it
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  9. Article
  10. Palliative Care in Neuro-oncology: an Update.Current neurology and neuroscience reports · 2023
    Review
  11. Review
  12. Malignant Glioma.Advances in experimental medicine and biology · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Patrick Y WenDivision of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital and Center for Neuro-Oncology, Dana-Farber Brigham and Women's Cancer Center, SW430D, 44 Binney Street, Boston, MA 02115, USA. pwen@partners.org
David Schiff
Santosh Kesari
Jan Drappatz
Debra C Gigas
Lisa Doherty
Brigham and Women's Hospital · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common medical problems in brain tumor patients include the management of seizures, peritumoral edema, medication side effects, venous thromboembolism (VTE), fatigue and cognitive dysfunction. Despite their importance, there are relatively few studies specifically addressing these issues. There is increasing evidence that brain tumor patients who have not had a seizure do not benefit from prophylactic antiepileptic medications. Patients on corticosteroids are at greater risk of Pneumocystis jerovecii pneumonia and may benefit from prophylactic therapy. There is also growing evidence suggesting that anticoagulation may be more effective than inferior vena cava IVC) filtration devices for treating VTE in brain tumor patients and the risk of hemorrhage with anticoagulation is relatively small. Low-molecular weight heparin may be more effective than coumadin. Medications such as modafinil and methylphenidate have assumed an increasing role in the treatment of fatigue, while donepezil and memantine may be helpful with memory loss.

Indexed as

Adrenal Cortex HormonesAnticoagulantsAnticonvulsantsBrain EdemaBrain NeoplasmsCognition DisordersDepressive DisorderEpilepsyFatigueHumansPatient Care PlanningVenous ThrombosisAdrenal Cortex HormonesAnticoagulantsAnticonvulsants

Identifiers

PMID16807780
OpenAlexW2033369193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.