SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2006
Intracranial aneurysms in children under 1 year of age: a systematic review of the literature.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Posttraumatic cerebrovascular injuries in children. A systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Pooled it
- Intracranial mycotic aneurysms in pediatric patients: A systematic review.Surgical neurology international · 2026Review
- Embolization of dissected and ruptured giant anterior cerebral artery aneurysm in a full-term neonate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Microsurgical management of a ruptured intracranial mycotic aneurysm in infancy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- A rare case of pediatric distal middle cerebral artery aneurysm.SAGE open medical case reports · 2024Article
- Ruptured Fusiform Anterior Cerebral Artery Aneurysm in an Infant : Case Report and a Literature Review.Journal of Korean Neurosurgical Society · 2023Article
- Should we screen for intracranial aneurysms in children with autosomal dominant polycystic kidney disease?Pediatric nephrology (Berlin, Germany) · 2023Article
- Successful treatment of ruptured multiple fusiform middle cerebral artery aneurysms with Silk Vista Baby flow diverter in a 10-month-old infant.BMJ case reports · 2022Article
- Extracranial-intracranial bypass in a neonate with multiple ruptured middle cerebral artery aneurysms: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Intracranial aneurysms in pediatric population treated with flow diverters: A single-center experience.Surgical neurology international · 2022Article
- A spontaneous dissecting posterior cerebral artery aneurysm in a 10-month-old female infant: a case report.Iranian journal of child neurology · 2022Article
- Onyx embolization of a ruptured anterior inferior cerebellar artery in a neonate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Alport's syndrome and intracranial aneurysm: mere coincidence or undiscovered causal relationship.BMJ case reports · 2019Article
- Management of infectious intracranial aneurysms in the pediatric population.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Infantile intracranial aneurysm of the superior cerebellar artery.BMJ case reports · 2016Article
- Radiological changes in infantile dissecting anterior communicating artery aneurysm treated endovascularly. A case report and five-year follow-up.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2014Article
- Intracranial Non-traumatic Aneurysms in Children and Adolescents.Current pediatric reviews · 2013Article
- Middle cerebral artery aneurysm in a premature neonate.Journal of Korean Neurosurgical Society · 2013Article
- De novo intracranial aneurysm formation following endovascular treatment of giant aneurysm in an infant: case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Three-year-old patient with giant MCA aneurysm treated by trapping-resection plus STA-MCA bypass. Case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIntracranial aneurysms are very rare in early childhood. Because the location, morphology as well as the clinical and radiological presentation of these aneurysms seem to be different from those in adults, we performed a systematic review of the literature to discuss the clinical, morphological, and radiological features of intracranial aneurysms in the first year of life. MATERIALS AND
methodsA computerized search of both Pubmed and EMBASE from before 1966 to 2005 was performed. Included were all articles that dealt with cases in which an intracranial aneurysm was demonstrated in children under 1 year of age.
resultsWe found 110 articles in which 131 cases of an intracranial aneurysm in children under 1 year were presented. The mean age at diagnosis of the aneurysm was 4.9+/-3.5 months with a male to female ratio of 1.1. There was a hemorrhagic presentation in 73% (n=96). The patients presenting with a hemorrhage were younger (mean 4.3 vs 6.7 months, P<0.001) and tended to have smaller-sized (i.e.<2.5 cm) aneurysms (P=0.07). The aneurysm was defined as traumatic or infectious in 15 and 13 cases, respectively. In 21% (n=27), there was various vascular or congenital co-morbidity. In 76%, the aneurysm was located in the anterior circulation. The prevalence of aneurysms on the middle cerebral artery (MCA) was nearly three times higher than on any other vessel. The mean aneurysm size was 1.8+/-1.4 cm, with 30 giant aneurysms (>2.5 cm). The giant aneurysms were significantly more often located in the posterior circulation (43 vs 16%, P=0.01). The mean period of follow-up was 13.6+/-24.8 months. The Glasgow Outcome Scale (GOS) could be derived in 106 cases: 50% had an excellent outcome (GOS of 5).
conclusionsThe presentation of arterial aneurysms in children under the age of 1 year differs from that in adults with a significantly higher prevalence of giant aneurysms in the posterior circulation. The prevalence of aneurysms on the MCA is nearly three times higher than on any other vessel. The patients presenting with a hemorrhage were younger and tended to have smaller-sized aneurysms. Our study did not confirm the male predominance that has thus far been associated with pediatric aneurysms. The outcome is comparable or slightly better than in adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.