ArticlePituitary2006
Phosphoproteomic analysis of the human pituitary.
Article in Pituitary, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Neuropeptides in the Extracellular Space of the Mouse Cortex Measured In Vivo by Nanodialysis Probe Coupled with LC-MS.Angewandte Chemie (International ed. in English) · 2025Article
- Phosphorylation of β-catenin at Serine552 correlates with invasion and recurrence of non-functioning pituitary neuroendocrine tumours.Acta neuropathologica communications · 2022Article
- Proteoglycan profiling of human, rat and mouse insulin-secreting cells.Glycobiology · 2021Article
- Article
- Targeting Nrf2-Mediated Oxidative Stress Response Signaling Pathways as New Therapeutic Strategy for Pituitary Adenomas.Frontiers in pharmacology · 2021Article
- Article
- Post-translational modifications of Hsp90 and translating the chaperone code.The Journal of biological chemistry · 2020Review
- Article
- Exploration of Molecular Network Variations in Different Subtypes of Human Non-functional Pituitary Adenomas.Frontiers in endocrinology · 2016Review
- Human Pituitary Adenoma Proteomics: New Progresses and Perspectives.Frontiers in endocrinology · 2016Review
- Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas.BMC medical genomics · 2014Article
- Proteome analysis of subsarcolemmal cardiomyocyte mitochondria: a comparison of different analytical platforms.International journal of molecular sciences · 2014Article
- Phosphoproteome mapping of cardiomyocyte mitochondria in a rat model of heart failure.Molecular and cellular biochemistry · 2014Article
- Secreted protein kinases.Trends in biochemical sciences · 2013Review
- Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry.Molecular & cellular proteomics : MCP · 2013Article
- Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients.Arthritis research & therapy · 2012Article
- A bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamics.Molecular bioSystems · 2010Article
- Endogenous peptide discovery of the rat circadian clock: a focused study of the suprachiasmatic nucleus by ultrahigh performance tandem mass spectrometry.Molecular & cellular proteomics : MCP · 2010Article
- Regulators affecting the metastasis suppressor activity of Nm23-H1.Molecular and cellular biochemistry · 2009Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The pituitary is the central endocrine gland that regulates the functions of various target organs in the human body. Because of the pivotal regulatory role of the pituitary, it is essential to define on a global scale the components of the pituitary protein machinery, including a comprehensive characterization of the post-translational modifications of the pituitary proteins. Of particular interest is the examination of the phosphorylation status of the pituitary in health and disease. Towards the goal of global profiling of pituitary protein phosphorylation, we report here the application of the in-gel IEF-LC-MS/MS approach to the study of the pituitary phosphoproteome. The analytical strategy combined isoelectric focusing in immobilized pH gradient strips with immobilized metal ion affinity chromatography and mass spectrometry. With this method, a total of 50 phosphorylation sites were characterized in 26 proteins. Because the investigation involved primary tissue, the findings provide a direct glimpse into the phosphoprotein machinery operating within the human pituitary tissue microenvironment.
Indexed as
Identifiers
16807684What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.