Evidence map›Paper›PMID 16807274›Full record

ArticleHeart (British Cardiac Society)2006

A population study of the long-term consequences of Rose angina: 20-year follow-up of the Renfrew-Paisley study.

N F Murphy, S Stewart, C L Hart, K MacIntyre, D Hole, J J V McMurray

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Article in Heart (British Cardiac Society), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

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  10. A novel prediction model for all cause emergency department visits in ischemic heart disease.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2011
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

N F MurphyDepartment of Cardiology, Western Infirmary, Glasgow G11 6NT, UK.
S Stewart
C L Hart
K MacIntyre
D Hole
J J V McMurray
Public Health Scotland · GBWestern Infirmary · GBThe Heart Research Institute · AUUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the long-term cardiovascular consequences of angina in a large epidemiological study.

designProspective cohort study conducted between 1972 and 1976 with 20 years of follow-up (the Renfrew-Paisley Study).

settingRenfrew and Paisley, West Scotland, UK.

participants7048 men and 8354 women aged 45-64 years who underwent comprehensive cardiovascular screening at baseline, including the Rose Angina Questionnaire and electrocardiography (ECG).

main outcome measuresAll deaths and hospitalisations for cardiovascular reasons occurring over the subsequent 20 years, according to the baseline Rose angina score and baseline ECG.

resultsAt baseline, 669 (9.5%) men and 799 (9.6%) women had angina on Rose Angina Questionnaire. All-cause mortality for those with Rose angina was 67.7% in men and 43.3% in women at 20 years compared with 45.4% and 30.4%, respectively, in those without angina (p<0.001). Values are expressed as hazards ratio (HR) (95% confidence interval (CI). In a multivariate analysis, men with Rose angina had an increased risk of cardiovascular death or hospitalisation (1.49 (1.33 to 1.66), myocardial infarction (1.63 (1.41 to 1.85)) or heart failure (1.54 (1.13 to 2.10)) compared with men without angina. The corresponding HR (95% CI) for women were 1.38 (1.23 to 1.55), 1.56 (1.31 to 1.85) and 1.92 (1.44 to 2.56). An abnormality on the electrocardiogram (ECG) increased risk further, and both angina and an abnormality on the ECG increased risk most of all compared with those with neither angina nor ischaemic changes on the ECG. Compared with men, women with Rose angina were less likely to have a cardiovascular event (0.54 (0.46 to 0.64)) or myocardial infarction (0.44 (0.35 to 0.56)), although there was no sex difference in the risk of stroke (1.11 (0.75 to 1.65)), atrial fibrillation (0.84 (0.38 to 1.87)) or heart failure (0.79 (0.51 to 1.21)).

conclusionsAngina in middle age substantially increases the risk of death, myocardial infarction, heart failure and other cardiovascular events.

Indexed as

Age DistributionAngina PectorisCohort StudiesElectrocardiographyFemaleHeart FailureHospitalizationHumansMaleMiddle AgedMyocardial InfarctionPrevalenceProspective StudiesRisk FactorsScotlandSurveys and Questionnaires

Identifiers

PMID16807274
PMCPMC1861298
OpenAlexW2161997841

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.