Evidence map›Paper›PMID 16806228›Full record

SynthesisAtherosclerosis2007

Aerobic exercise and lipids and lipoproteins in children and adolescents: a meta-analysis of randomized controlled trials.

George A Kelley, Kristi S Kelley

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Atherosclerosis, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
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  14. The impacts of exercise on pediatric obesity.Clinical and experimental pediatrics · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

George A KelleySchool of Medicine, Department of Community Medicine, West Virginia University, Morgantown, WV 26506-9190, USA. gkelley@hsc.wvu.edu
Kristi S Kelley
West Virginia University · US

Funding

Aerobic Exercise, Diet and Cholesterol: A Meta-AnalysisR01HL069802 · NHLBI · WEST VIRGINIA UNIVERSITY · PI KELLEY, GEORGE A · 2002 to 2010
$866k
NHLBI NIH HHS R01 HL069802NHLBI NIH HHS R01-HL069802
6 · The paper itself

Abstract

objectiveUse the meta-analytic approach to examine the effects of aerobic exercise on total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) in children and adolescents. STUDY

designRandomized controlled trials which were limited to aerobic exercise >or=4 weeks in children and adolescents 5-19 years of age.

resultsTwelve outcomes representing 389 subjects were available for pooling. Using random-effects modeling, a trend for statistically significant decreases of 12% was found for TG (X +/-S.E.M., -11.0+/-6.1mg/dl; 95% CI, -22.8-0.8 mg/dl) with no statistically significant changes for TC, HDL-C, and LDL-C. Decreases in LDL-C were associated with increased training intensity (r=-0.89; 99% CI, -0.99 to -0.04) and older age (r=-0.90; 99% CI, -0.99 to -0.25) while increases in HDL-C were associated with lower initial HDL-C (r=-0.75; 99% CI, -0.94 to -0.80). Statistically significant decreases in TG were observed in overweight/obese subjects with a trend for increases in HDL-C (TG, X +/-S.E.M., -23.9+/-7.0mg/dl; 95% CI, -37.6 to -10.1mg/dl; HDL-C, X +/-S.E.M., 4.0+/-2.3mg/dl; 95% CI, -0.5-8.5mg/dl).

conclusionsAerobic exercise decreases TG in overweight/obese children and adolescents.

Indexed as

ExerciseAdolescentChildCholesterolCholesterol, HDLCholesterol, LDLHumansLipidsLipoproteinsObesityTriglyceridesCholesterolCholesterol, HDLCholesterol, LDLLipidsLipoproteinsTriglycerides

Identifiers

PMID16806228
PMCPMC2447165
OpenAlexW2070361896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.