ArticleJournal of perinatology : official journal of the California Perinatal Association2006
Early and aggressive nutritional strategy (parenteral and enteral) decreases postnatal growth failure in very low birth weight infants.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 181 citations in OpenAlex.
- Individualized Target Fortification of Breast Milk with Protein, Carbohydrates, and Fat for Preterm Infants: Effect on Neurodevelopment.Nutrients · 2025Trial
- The "Fortilat" Randomized Clinical Trial Follow-Up: Neurodevelopmental Outcome at 18 Months of Age.Nutrients · 2020Trial
- The "Fortilat" Randomized Clinical Trial Follow-Up: Auxological Outcome at 18 Months of Age.Nutrients · 2020Trial
- A Novel Donkey Milk-derived Human Milk Fortifier in Feeding Preterm Infants: A Randomized Controlled Trial.Journal of pediatric gastroenterology and nutrition · 2019Trial
- Trial
- Enhanced feeding and diminished postnatal growth failure in very-low-birth-weight infants.Journal of pediatric gastroenterology and nutrition · 2014Trial
- Trial
- Early nutrition mediates the influence of severity of illness on extremely LBW infants.Pediatric research · 2011Trial
- N-Acetyltyrosine as a Biomarker of Parenteral Nutrition Administration in First-Tier Newborn Screening Assays.International journal of neonatal screening · 2024Article
- Early postnatal growth failure in infants <1500 g in a Ugandan referral hospital: a retrospective cohort study.BMC pediatrics · 2024Article
- Postnatal growth failure of very low-birth-weight infants in Southwest Iran: A descriptive analytical study.Health science reports · 2024Article
- The effects of maternal voice on pain during placement of peripherally inserted central catheter in neonates.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Article
- Article
- Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model.American journal of physiology. Endocrinology and metabolism · 2021Article
- The glucose infusion rate of parenteral nutrition in the first week of life in preterm infants: an observational study.Italian journal of pediatrics · 2021Observational
- Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver.Scientific reports · 2021Article
- Antenatal and neonatal factors contributing to extra uterine growth failure (EUGR) among preterm infants in Boston Birth Cohort (BBC).Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Characteristics and risk factors for extrauterine growth retardation in very-low-birth-weight infants.Medicine · 2020Article
- Factors associated with early phosphate levels in preterm infants.European journal of pediatrics · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare postnatal growth and nutritional deficits after the implementation of two different nutritional strategies in two consecutives periods of time.
methodsAn early and aggressive nutritional regimen was used in a cohort of 117 very low birth weight (VLBW) infants. Amino acids were administered at the rate of 1.5 g/kg/day along with 5.6 mg/k/min of glucose flow on day 1 of life, and progressively increased to 4 g/kg/day and 13 mg/kg/min. Intravenous lipids were started at 0.5 g/kg/day at 24 h from birth, and increased to 3.5 g/kg/day; enteral feeding was begun at day 1 of life. Uni- and multivariate analyses were used to compare this group with the conventional group of 65 VLBW infants conservatively fed.
resultsUnivariate analysis showed that in the aggressive group there was a 66% reduction in the risk of post natal malnutrition at 40 weeks of postmenstrual age (OR 0.34; 95% CI 0.17-0.67). This difference persisted in the multivariate analysis. Energy and protein deficits were lower in the aggressive group (P < 0.001).
conclusionsEarly and aggressive introduction of total parenteral nutrition and enteral feeding resulted in better growth in weight, length and head circumference, and a reduction of nutritional deficits at 40 weeks of postmenstrual age.
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