ArticlePathology oncology research : POR2006
HLA class II polymorphism: protective or risk factors to breast cancer in Tunisia?
Article in Pathology oncology research : POR, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Specific HLA-DQB1 alleles associated with risk for development of hepatocellular carcinoma: a meta-analysis.World journal of gastroenterology · 2011Pooled it
- Carriage of HLA-DRB1*11 and 1*12 alleles and risk factors in patients with breast cancer in Burkina Faso.Open life sciences · 2021Article
- A Review of Cancer Genetics and Genomics Studies in Africa.Frontiers in oncology · 2020Review
- Association between DLA-DRB1.2 allelic diversity and development of mammary gland tumors in dogs.Acta veterinaria Scandinavica · 2019Article
- Downregulation of CD99 and upregulation of human leukocyte antigen class II promote tumor aggravation and poor survival in patients with osteosarcomas.OncoTargets and therapy · 2014Article
- HLA class-II allele frequencies in Turkish breast cancer patients.Medical oncology (Northwood, London, England) · 2012Article
- HLA-DRB1,-DQA1 and -DQB1 allele and haplotype frequencies in female patients with early onset breast cancer.Pathology oncology research : POR · 2012Article
- Article
- Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.Human genetics · 2008Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HLA system plays a key role in the tumor cells' escape from immune surveillance. Herein is the first report on the correlation of the susceptibility to breast cancer with HLA class II markers in Tunisia. Molecular typing of HLA-DRB1 and -DQB1 loci was undertaken for 70 Tunisian female patients. Comparison of allele and haplotype distribution between patients and 70 female control subjects reveals a negative association between HLADRB1* 07-DQB1*02 and the incidence of breast cancer in the Tunisian population.
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Registered trials
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