Evidence map›Paper›PMID 16799128›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Types of unintended consequences related to computerized provider order entry.

Emily M Campbell, Dean F Sittig, Joan S Ash, Kenneth P Guappone, Richard H Dykstra

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01262053 (Investigating Wrong-Patient CPOE Errors), which is not on this map. Cited by 276 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
276citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01262053 nacompletednot on this map

Investigating Wrong-Patient CPOE Errors

TypeinterventionalSponsorMontefiore Medical CenterRan2010 to 2011Enrolled4,028ConditionsWrong Patient Computerized Physician Order Entry ErrorsArmsPassive Intervention, Active Intervention, Control
3 · Its place in the literature

Who cites it

276 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Effect of electronic drug-drug interaction alerts on patient and clinician outcomes: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2025
    Pooled it
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  9. Does user-centred design affect the efficiency, usability and safety of CPOE order sets?Journal of the American Medical Informatics Association : JAMIA · 2011
    Trial
  10. Article
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  14. Evaluation of Health Professions Trainee Experiences Transitioning to New VHA Electronic Health Record.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2026
    Article
  15. Article
  16. Article
  17. Development and application of desiderata for automated clinical ordering.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  18. Review
  19. Article
  20. Article

216 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Emily M CampbellDepartment of Medical Informatics and Clinical Epidemiology, Portland, OR 97239-3098, USA.
Dean F Sittig
Joan S Ash
Kenneth P Guappone
Richard H Dykstra

Funding

Unintended Consequences of Physician Order EntryR01LM006942 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI ASH, JOAN S. · 2000 to 2010
$4.0M
Clinical Decision Support in Community Hospitals: Barriers & FacilitatorsR56LM006942 · NLM · OREGON HEALTH & SCIENCE UNIVERSITY · PI ASH, JOAN S. · 2007 to 2007
$461k
NLM NIH HHS LM06942NLM NIH HHS R01 LM006942NLM NIH HHS R56 LM006942PHS HHS ASMM10031
6 · The paper itself

Abstract

objectiveTo identify types of clinical unintended adverse consequences resulting from computerized provider order entry (CPOE) implementation.

designAn expert panel provided initial examples of adverse unintended consequences of CPOE. The authors, using qualitative methods, gathered and analyzed additional examples from five successful CPOE sites.

methodsUsing a card sort method, the authors developed a categorization scheme for the 79 unintended consequences initially identified and then iteratively modified the scheme to categorize 245 additional adverse consequences resulting from fieldwork. Because the focus centered on consequences requiring prevention or remedial action, the authors did not further analyze reported unintended beneficial (positive) consequences.

resultsUnintended adverse consequences (UACs) fell into nine major categories (in order of decreasing frequency): 1) more/new work for clinicians; 2) unfavorable workflow issues; 3) never ending system demands; 4) problems related to paper persistence; 5) untoward changes in communication patterns and practices; 6) negative emotions; 7) generation of new kinds of errors; 8) unexpected changes in the power structure; and 9) overdependence on the technology. Clinical decision support features introduced many of these unintended consequences.

conclusionIdentifying and understanding the types and in some instances the causes of unintended adverse consequences associated with CPOE will enable system developers and implementers to better manage implementation and maintenance of future CPOE projects.

Indexed as

Medical Order Entry SystemsOrganizational InnovationCommunicationHumansMedical ErrorsOrganizational CultureWorkload

Identifiers

PMID16799128
PMCPMC1561794

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.