ArticleProceedings of the National Academy of Sciences of the United States of America2006
Os8N3 is a host disease-susceptibility gene for bacterial blight of rice.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 279 papers, 1 of them a synthesis that pooled it.
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Who cites it
279 citing papers in PubMed, 1 synthesis or guideline pooled it, 621 citations in OpenAlex.
- Conventional and new-breeding technologies for improving disease resistance in lentil (Frontiers in plant science · 2022Pooled it
- Dodder seedlings benefit from apoplastic nutrition by inducing SWEET15-mediated unloading of sucrose from the host's phloem.The New phytologist · 2026Article
- Negative Regulators of Rice Agronomic Traits: Functional Insights and Applications in Genome Editing-Based Breeding.Plant biotechnology journal · 2026Review
- Control Targets in Plant-Pathogenic Bacteria: From Growth-Essential Processes to Anti-Virulence Strategies and Candidate Targets inPlants (Basel, Switzerland) · 2026Review
- Guardians or Gateways? The Intricate Relationship Between Plant Cell Walls and Pathogenic Xanthomonas.Molecular plant pathology · 2026Review
- Effector Triggered Susceptibility and Immunity in Bacterial Diseases of Leaf Blight and Streak in Rice.Rice (New York, N.Y.) · 2026Review
- Strigolactones Regulate Sugar Allocation to Control Rice Tillering and Root Development via the OsSPL14-OsSHR1-OsSWEET16 Pathway.Plant biotechnology journal · 2026Article
- Targeting dCas9-SunTag to a Susceptibility Gene Promoter Is Sufficient for CRISPR Interference.Plant direct · 2026Article
- PyramidingPlants (Basel, Switzerland) · 2026Article
- Take control of expression: effector-mediated modulation of the host transcriptional machinery.Frontiers in plant science · 2026Review
- Isolation of AtSWEET Membrane Proteins from Arabidopsis Leaves for Host-Pathogen Interaction Studies.Methods in molecular biology (Clifton, N.J.) · 2026Article
- A critical role ofPNAS nexus · 2026Article
- Overexpression ofPlant signaling & behavior · 2025Article
- CRISPR-Cas9 based editing of the susceptibility allele TaLr34 enhances leaf rust resistance in bread wheat without yield penalty.Functional & integrative genomics · 2025Article
- Regulatory balance between ear rot resistance and grain yield and their breeding applications in maize and other crops.Journal of advanced research · 2025Review
- Ustilago maydis Nit2 Regulates Nitrate Utilisation During Biotrophy and Affects Amino Acid Metabolism of Galls Under Nitrogen Depletion.Molecular plant pathology · 2025Article
- Transcription activator-like effectors of Xanthomonas oryzae pv. oryzae hijack host transcriptional regulation through OsWRKYs.Journal of integrative plant biology · 2025Article
- Sucrose transport gene FaSWEET9a regulated by FaDOF2 transcription factor promotes sucrose accumulation in strawberry.Plant cell reports · 2025Article
- Mutations in the SWEET15 Sugar Transporter Gene Affect Response of Citrus to Huanglongbing Disease and Citrus Canker.Molecular plant pathology · 2025Article
- Recent Progress in Rice-Biology · 2025Review
219 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Many bacterial diseases of plants depend on the interaction of type III effector genes of the pathogen and disease-susceptibility genes of the host. The host susceptibility genes are largely unknown. Here, we show that expression of the rice gene Os8N3, a member of the MtN3 gene family from plants and animals, is elevated upon infection by Xanthomonas oryzae pv. oryzae strain PXO99(A) and depends on the type III effector gene pthXo1. Os8N3 resides near xa13, and PXO99(A) failed to induce Os8N3 in rice lines with xa13. Silencing of Os8N3 by inhibitory RNA produced plants that were resistant to infection by strain PXO99(A) yet remained susceptible to other strains of the pathogen. The effector gene avrXa7 from strain PXO86 enabled PXO99(A) compatibility on either xa13- or Os8N3-silenced plants. The findings indicate that Os8N3 is a host susceptibility gene for bacterial blight targeted by the type III effector PthXo1. The results support the hypothesis that X. oryzae pv. oryzae commandeers the regulation of otherwise developmentally regulated host genes to induce a state of disease susceptibility. Furthermore, the results support a model in which the pathogen induces disease susceptibility in a gene-for-gene manner.
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