Evidence map›Paper›PMID 16798756›Full record

ArticleBMJ (Clinical research ed.)2006

Mortality after Staphylococcus aureus bacteraemia in two hospitals in Oxfordshire, 1997-2003: cohort study.

David H Wyllie, Derrick W Crook, Tim E A Peto

Erratum issuedOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 211 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Factors associated with methicillin resistance in Staphylococcus aureus: a case-case-control analysis of AMR surveillance data.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Intracellular Habitation ofBiomedicines · 2022
    Review
  10. Vegetation Formation inFrontiers in cellular and infection microbiology · 2022
    Article
  11. Review
  12. Adherence to a care bundle forSouthern African journal of infectious diseases · 2022
    Article
  13. Article
  14. SFRSC medicinal chemistry · 2021
    Article
  15. Article
  16. Article
  17. Public Health Importance of Invasive Methicillin-sensitive Staphylococcus aureus Infections: Surveillance in 8 US Counties, 2016.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  18. Article
  19. Biofilm Formation byJournal of clinical medicine · 2019
    Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David H WyllieNuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU. david.wyllie@ndcls.ox.ac.uk
Derrick W Crook
Tim E A Peto
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the incidence of methicillin resistant and methicillin sensitive Staphylococcus aureus (MRSA and MSSA) bacteraemia in inpatients and associated mortality within 30 days after diagnosis.

designAnonymised record linkage study of data from hospital information systems and microbiology databases.

settingTeaching hospital and district general hospital in Oxfordshire.

participantsInpatients aged 18 or over admitted to a teaching hospital between 1 April 1997 and 31 March 2004 and to a district general hospital between 1 April 1999 and 31 March 2004. The main part of the study comprised 216 644 inpatients; patients admitted to haematology, nephrology, or oncology services were not included because most were managed as outpatients. OUTCOME MEASURES: Nosocomial MSSA and MRSA bacteraemia; death in hospital within 30 days after bacteraemia.

resultsRates of S aureus bacteraemia rose between 1997 and 2003, and MRSA was responsible for this increase. Overall mortality 30 days after bacteraemia was 29%. The crude odds ratio for death after MRSA bacteraemia compared with MSSA bacteraemia was 1.49 (95% confidence interval 0.99 to 2.26).

conclusionThe spread of MRSA has greatly increased the overall number of cases of S aureus bacteraemia and has contributed to short term mortality after S aureus bacteraemia.

Indexed as

Hospital MortalityMethicillin ResistanceStaphylococcus aureusAdolescentAdultAgedAnti-Bacterial AgentsBacteremiaCohort StudiesCross InfectionEnglandHospitals, DistrictHospitals, GeneralHospitals, TeachingHumansIncidenceAnti-Bacterial AgentsMethicillin

Identifiers

PMID16798756
PMCPMC1526943
OpenAlexW1991773594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.