ArticleJournal of neuroimmunology2006
Longitudinal analysis of activation markers on monocyte subsets during the development of simian immunodeficiency virus encephalitis.
Article in Journal of neuroimmunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Review
- Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment.Retrovirology · 2018Article
- Toll-like receptor 2Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2017Article
- Paving the path to HIV neurotherapy: Predicting SIV CNS disease.European journal of pharmacology · 2015Review
- Spatiotemporal dynamics of simian immunodeficiency virus brain infection in CD8+ lymphocyte-depleted rhesus macaques with neuroAIDS.The Journal of general virology · 2014Article
- Astrocyte and macrophage regulation of YKL-40 expression and cellular response in neuroinflammation.Brain pathology (Zurich, Switzerland) · 2012Article
- Expansion of a subset of CD14highCD16negCCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection.Journal of leukocyte biology · 2012Article
- Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals.PloS one · 2011Article
- Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS.Cellular immunology · 2011Article
- Endothelial cell suppression of peripheral blood mononuclear cell trafficking in vitro during acute exposure to feline immunodeficiency virus.Cell and tissue research · 2008Article
- Increased expression of monocyte CD44v6 correlates with the deveopment of encephalitis in rhesus macaques infected with simian immunodeficiency virus.The Journal of infectious diseases · 2008Article
- Longitudinal in vivo positron emission tomography imaging of infected and activated brain macrophages in a macaque model of human immunodeficiency virus encephalitis correlates with central and peripheral markers of encephalitis and areas of synaptic degeneration.The American journal of pathology · 2008Article
- Systemic and brain macrophage infections in relation to the development of simian immunodeficiency virus encephalitis.Journal of virology · 2008Article
- NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS.Molecular diagnosis & therapy · 2008Review
- Neuroinvasion of fluorescein-positive monocytes in acute simian immunodeficiency virus infection.Journal of virology · 2007Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Lentiviral encephalitis has been hypothesized to be associated with altered monocyte migration into the brain. CD14(hi)/CD16(lo) and CD14(lo)/CD16(hi) monocytes were expanded during acute infection; however, this expansion was not unique or greater in macaques that developed encephalitis. The proportion of monocytes that expressed CD62L, HLA-DR, CD16, CD64, and CD40 varied during the course of infection in macaques that eventually developed encephalitis. Taken together, these results suggest that changes in the proportion of circulating activated monocytes are not predictive of development of encephalitis, but this does not rule out the importance of activated monocytes in the development of encephalitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.