ReviewJournal of cellular and molecular medicine
Clinical and therapeutical implications of EPC biology in atherosclerosis.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Review
- Steroid-Induced Osteonecrosis of the Femoral Head: Novel Insight Into the Roles of Bone Endothelial Cells in Pathogenesis and Treatment.Frontiers in cell and developmental biology · 2021Review
- Impairment of circulating endothelial progenitor cells (EPCs) in patients with glucocorticoid-induced avascular necrosis of the femoral head and changes of EPCs after glucocorticoid treatment in vitro.Journal of orthopaedic surgery and research · 2019Article
- Effects of Extra Virgin Olive Oil and Apples Enriched-Dark Chocolate on Endothelial Progenitor Cells in Patients with Cardiovascular Risk Factors: A Randomized Cross-Over Trial.Antioxidants (Basel, Switzerland) · 2019Article
- Resveratrol protects late endothelial progenitor cells from TNF-α-induced inflammatory damage by upregulating Krüppel-like factor-2.Molecular medicine reports · 2018Article
- Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration.Stem cells international · 2016Review
- Differential gene expression in Lin-/VEGF-R2+ bone marrow-derived endothelial progenitor cells isolated from diabetic mice.Cardiovascular diabetology · 2014Article
- Endothelial progenitor cells in acute ischemic stroke.Brain and behavior · 2013Article
- Stem cell therapy to protect and repair the developing brain: a review of mechanisms of action of cord blood and amnion epithelial derived cells.Frontiers in neuroscience · 2013Review
- Endothelial progenitor cells are related to glycemic control in children with type 1 diabetes over time.Diabetes care · 2013Article
- Article
- Mobilization of endothelial progenitors by recurrent bacteremias with a periodontal pathogen.PloS one · 2013Article
- Endothelial progenitor cells: the promise of cell-based therapies for acute lung injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2013Review
- In vitro labeling of endothelial progenitor cells isolated from peripheral blood with superparamagnetic iron oxide nanoparticles.Molecular medicine reports · 2012Article
- Endothelial progenitor cells in atherosclerosis.Frontiers in bioscience (Landmark edition) · 2012Review
- Thromboresistant and endothelialization effects of dopamine-mediated heparin coating on a stent material surface.Journal of materials science. Materials in medicine · 2012Article
- Dysfunctional endothelial progenitor cells in metabolic syndrome.Experimental diabetes research · 2012Review
- Opposing effects of monomeric and pentameric C-reactive protein on endothelial progenitor cells.Basic research in cardiology · 2011Article
- In vivo serial MR imaging of magnetically labeled endothelial progenitor cells homing to the endothelium injured artery in mice.PloS one · 2011Article
- Circulating levels of endothelial progenitor cell mobilizing factors in the metabolic syndrome.The American journal of cardiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone marrow-derived circulating endothelial progenitor cells have been successfully used to enhance angiogenesis after tissue ischemia. The role of endothelial progenitor cells in endothelial cell homeostasis and their putative role in atherogenesis have been recently investigated. Cardiovascular risk factors negatively influence endothelial progenitor cell number and function while vasculoprotection e.g. by statins, estrogens and physical activity may be partly mediated by progenitor cells. Endogenous mobilization or injection of ex-vivo generated endothelial progenitor cells is associated with an enhanced reendothelialization, an improvement of endothelial function and reduced atherosclerotic burden. In contrast, endothelial progenitor cells may promote plaque angiogenesis in animal models and may negatively influence plaque development and stability. However, in humans with coronary atherosclerotic disease, endothelial progenitor cells are a novel risk predictor for cardiovascular mortality and morbidity. In this review we focus on the role of circulating endothelial progenitor cells in endothelial cell repair mechanisms at the vascular wall and their potentially protective and therapeutic role in atherosclerotic disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.