ArticleAnnals of surgery2006
Right portal vein embolization before right hepatectomy for unilobar colorectal liver metastases reduces the intrahepatic recurrence rate.
Article in Annals of surgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Cryotherapy for liver metastases.The Cochrane database of systematic reviews · 2019Pooled it
- Portal Vein Embolization: Rationale, Techniques, and Outcomes to Maximize Remnant Liver Hypertrophy with a Focus on Contemporary Strategies.Life (Basel, Switzerland) · 2023Review
- Improved liver function after portal vein embolization and an elective right hepatectomy.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015Article
- Predicting early intrahepatic recurrence after curative resection of colorectal liver metastases with molecular markers.World journal of surgery · 2015Article
- Portal vein embolization and ligation for extended hepatectomy.Indian journal of surgical oncology · 2014Review
- Portal vein embolization improves rate of resection of extensive colorectal liver metastases without worsening survival.The British journal of surgery · 2013Article
- One-stage hepatectomy following portal vein embolization for colorectal liver metastasis.World journal of surgery · 2013Article
- Prolonged portal triad clamping increases postoperative sepsis after major hepatectomy in patients with sinusoidal obstruction syndrome and/or steatohepatitis.World journal of surgery · 2012Article
- Impact of biomarkers expression before and after portal vein embolization on recurrence after two-stage hepatectomy for colorectal liver metastases.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
- Sinusoidal obstruction syndrome compromises liver regeneration in patients undergoing two-stage hepatectomy with portal vein embolization.Surgery today · 2011Article
- Outcomes of simultaneous and delayed resections of synchronous colorectal liver metastases.Canadian journal of surgery. Journal canadien de chirurgie · 2009Article
- Intrahepatic lymphatic invasion independently predicts poor survival and recurrences after hepatectomy in patients with colorectal carcinoma liver metastases.Annals of surgical oncology · 2007Article
- [Colorectal liver metastases. Neoadjuvant chemotherapy: aspects of medical and surgical oncology].Der Internist · 2007Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the effect of portal vein embolization (PVE) on intrahepatic recurrence rate after right hepatectomy for unilobar colorectal liver metastases (CLM). SUMMARY AND
backgroundRecent research suggests that CLM could spread retrogradely through the portal vein. PVE may reduce tumor shedding by the occlusion of distal portal branches. However, no study reported the clinical effect of PVE on intrahepatic recurrence after CLM resection. PATIENTS AND
methodsBetween 1995 and 2003, 44 patients requiring a right hepatectomy for unilobar CLM were operated in our institution. Right hepatectomy was performed after PVE in 23 patients (group A) and without PVE in 21 (group B). Surgical outcome and site of recurrence were analyzed.
resultsThe postoperative mortality was nil. Overall morbidity and transitory liver failure rates were similar in groups A and B (43.4% and 17.3% vs. 33.3% and 14.2%, respectively). The 3- and 5-year overall survival rates did not differ in group A and B patients (61.2% and 43.7% vs. 49.7% and 35.5%, respectively; P = 0.862). The disease-free survival rate was similar in both groups. Thirty patients (68.2%) developed recurrences. Recurrences were intrahepatic in 22 patients (50%) and extrahepatic in 27 (61.3%). Intrahepatic recurrence rate was significantly lower in group A compared with group B (26.0% vs. 76.1% respectively; P < 0.001). PVE, number of CLM, and administration of neoadjuvant chemotherapy were independent prognostic factors for intrahepatic recurrences.
conclusionThis study showed that PVE reduces intrahepatic recurrence rate after right hepatectomy for unilobar CLM.
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