ArticleBiochemical genetics1991
A molecular genetic linkage map of mouse chromosome 18, including spm, Grl-1, Fim-2/c-fms, and Mbp.
Article in Biochemical genetics, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Corticotropin-releasing hormone affects short immobilization stress-induced changes in lung cytosolic and membrane glucocorticoid binding sites.Cellular and molecular neurobiology · 2013Article
- Early steps in steroidogenesis: intracellular cholesterol trafficking.Journal of lipid research · 2011Review
- Recent advances in elucidating Niemann-Pick C disease.Brain pathology (Zurich, Switzerland) · 1998Review
- Substantial narrowing of the Niemann-Pick C candidate interval by yeast artificial chromosome complementation.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- High-resolution mapping of the spm (Niemann-Pick Type C) locus on mouse chromosome 18.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Restoration of the cholesterol metabolism in 3T3 cell lines derived from the sphingomyelinosis mouse (spm/spm) by transfer of a human chromosome 18.Human genetics · 1993Article
- Linkage of Niemann-Pick disease type C to human chromosome 18.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- A molecular genetic linkage map of mouse chromosome 10, including the Myb, S100b, Pah, Sl, and Ifg genes.Biochemical genetics · 1992Article
- Mouse chromosome 18.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- A molecular genetic linkage map of mouse chromosome 19, including the lpr, Ly-44, and Tdt genes.Biochemical genetics · 1991Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restriction endonuclease fragment length variations (RFLV) were detected in mice with DNA probes for myelin basic protein (Mbp), glucocorticoid receptor-1 (Grl-1), and Friend MuLV integration site-2 (Fim-2). RFLV of the Mbp gene were found in SacI restriction patterns, RFLV of the Grl-1 gene were found in EcoRV patterns, and RFLV of the Fim-2 were found in BglII patterns. A three-point backcross was carried out by the backcross mating (C57BL/KsJ-spm/spm x MOL-MIT)F1 males x C57BL/KsJ-spm/spm; spm is an autosomal recessive gene causing sphingomyelinosis. From the results, spm, Grl-1, Fim-2, and Mbp loci were mapped on chromosome 18, and the following order of genes is proposed, with distances between genes in parentheses: centromere--spm--(7.8 cM)--Grl-1--(7.8 cM)--Fim-2--(39.1 cM)--Mbp--telomere. All laboratory strains and two European subspecies (Mus mus domesticus and M. m. brevirostris) carry the Grl-1a, Fim-2a, and Mbpa alleles. In contrast, another wild subspecies from Europe (M. m. musculus) and some Asian subspecies (M. m. molossinus, Chinese mice of wild origin, and M. m. yamashinai) carry the Grl-1b, Fim-2b, and Mbpb alleles. Only castaneus strains carry the intermediate combination of the Grl-1b, Fim-2a, and Mbpb alleles.
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