Evidence map›Paper›PMID 16791662›Full record

GuidelineIntensive care medicine2006

Fluid resuscitation in neonatal and pediatric hypovolemic shock: a Dutch Pediatric Society evidence-based clinical practice guideline.

Nicole Boluyt, Casper W Bollen, Albert P Bos, Joke H Kok, Martin Offringa

Open access · bronzeAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Fluid management in children with volume depletion.Pediatric nephrology (Berlin, Germany) · 2024
    Review
  5. Article
  6. Umbilical cord milking at birth for term newborns with acidosis: neonatal outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Article
  7. Review
  8. Article
  9. Article
  10. Pre-hospital care of pediatric patients with trauma.International journal of critical illness and injury science · 2012
    Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nicole BoluytDepartment of Pediatric Clinical Epidemiology, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands. n.boluyt@amc.uva.nl
Casper W Bollen
Albert P Bos
Joke H Kok
Martin Offringa
Emma Kinderziekenhuis · NLUniversity of Amsterdam · NLWilhelmina Children's Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a clinical practice guideline that provides recommendations for the fluid, i.e. colloid or crystalloid, used for resuscitation in critically ill neonates and children up to the age of 18 years with hypovolemia.

methodsThe guideline was developed through a comprehensive search and analysis of the pediatric literature. Recommendations were formulated by a national multidisciplinary committee involving all stakeholders in neonatal and pediatric intensive care and were based on research evidence from the literature and, in areas where the evidence was insufficient or lacking, on consensus after discussions in the committee.

resultsBecause of the lack of evidence in neonates and children, trials conducted in adults were considered. We found several recent meta-analyses that show excess mortality in albumin-treated groups, compared with crystalloid-treated groups, and one recent large randomized controlled trial that found evidence of no mortality difference. We found no evidence that synthetic colloids are superior to crystalloid solutions.

conclusionsGiven the state of the evidence and taking all other considerations into account, the guideline-developing group and the multidisciplinary committee recommend that in neonates and children with hypovolemia the first-choice fluid for resuscitation should be isotonic saline.

Indexed as

ChildChild, PreschoolCrystalloid SolutionsEvidence-Based MedicineFluid TherapyHumansHypovolemiaInfantInfant, NewbornIsotonic SolutionsNetherlandsPediatricsPractice Patterns, Physicians'Rehydration SolutionsResuscitationShockCrystalloid SolutionsIsotonic SolutionsRehydration Solutions

Identifiers

PMID16791662
OpenAlexW2122366462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.