ArticleDiabetologia2006
Relationships of physical activity with metabolic syndrome features and low-grade inflammation in adolescents.
Article in Diabetologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.
- Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2012Pooled it
- A short-term diet and exercise intervention ameliorates inflammation and markers of metabolic health in overweight/obese children.American journal of physiology. Endocrinology and metabolism · 2012Trial
- A cluster randomised school-based lifestyle intervention programme for the prevention of childhood obesity and related early cardiovascular disease (JuvenTUM 3).BMC public health · 2011Trial
- A cross-curricular physical activity intervention to combat cardiovascular disease risk factors in 11-14 year olds: 'activity knowledge circuit'.BMC public health · 2009Trial
- Association between physical activity and visceral adiposity index (VAI) in U.S. population with overweight or obesity: a cross-sectional study.BMC public health · 2024Article
- Gender differences in the distribution of children's physical activity: evidence from nine countries.The international journal of behavioral nutrition and physical activity · 2023Article
- Longitudinal reallocations of time between 24-h movement behaviours and their associations with inflammation in children and adolescents: the UP&DOWN study.The international journal of behavioral nutrition and physical activity · 2023Article
- Duration, timing, and consistency of sleep in relation to inflammatory cytokines in Mexican adolescents.Sleep medicine · 2022Article
- Use of Physical Activity and Exercise to Reduce Inflammation in Children and Adolescents with Obesity.International journal of environmental research and public health · 2022Review
- Low leptin levels are associated with elevated physical activity among lean school children in rural Tanzania.BMC public health · 2022Article
- Systemic Inflammation, Oxidative Stress and Cardiovascular Health in Children and Adolescents: A Systematic Review.Antioxidants (Basel, Switzerland) · 2022Review
- C-Reactive Protein and TGF-α Predict Psychological Distress at Two Years of Follow-Up in Healthy Adolescent Boys: The Fit Futures Study.Frontiers in psychology · 2022Article
- Examination of Self-Esteem, Body Image, Eating Attitudes and Cardiorespiratory Performance in Adolescents.International journal of environmental research and public health · 2021Article
- Association between Obesity and Overweight and Cardiorespiratory and Muscle Performance in Adolescents.International journal of environmental research and public health · 2020Article
- Physical activity, sedentary time and cardiometabolic health indicators among Mexican children.Clinical obesity · 2020Article
- Multi-Stage Fitness Test Performance,Frontiers in physiology · 2019Article
- Trajectories of maternal leisure-time physical activity and sedentary behavior during adolescence to young adulthood and offspring birthweight.Annals of epidemiology · 2017Article
- Associations of Vigorous-Intensity Physical Activity with Biomarkers in Youth.Medicine and science in sports and exercise · 2017Article
- Metabolic Syndrome and Cardiovascular Risk Factors in Obese Adolescent.Open access Macedonian journal of medical sciences · 2016Article
- Myokines in Response to a Tournament Season among Young Tennis Players.BioMed research international · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisPhysical activity has beneficial effects on symptoms of the metabolic syndrome and low-grade inflammation in adults. These associations have rarely been studied in adolescents. Moreover, it has not been established whether they depend on adiposity, fat localisation and adipokines. SUBJECTS, MATERIALS AND
methodsWe used cross-sectional data of 640 12-year-old adolescents participating in the Intervention Centred on Adolescents' Physical Activity and Sedentary Behaviour Study (ICAPS). Weight, height, body fat mass and WHR were measured. Metabolic syndrome components, two inflammatory markers (IL-6 and C-reactive protein), plasma leptin, adiponectin and soluble TNF-alpha receptor 1 (sTNF-alpha R1) were determined. Insulin resistance was estimated by homeostasis model assessment (HOMA) and energy expenditure due to organised leisure-time physical activity (PAE) assessed by questionnaire.
resultsThe metabolic syndrome was present in 5.8% of the adolescents. After adjustment for sex, sexual maturity and socio-economic status, a beneficial relationship between PAE and all metabolic syndrome features was found, but only the associations with HOMA and IL-6 were independent of body fat mass and WHR. Adjusted means from the lowest to the highest tertile of PAE were 1.99, 1.80 and 1.78 for HOMA (p=0.04), and 0.88, 0.69 and 0.70 pg/ml for IL-6 (p=0.02). PAE was inversely associated with leptin, independently of body fat mass and WHR (p<10(-2)), but not with adiponectin or sTNF-alpha R1. Further adjustment for adipokines did not change the relationships of PAE with HOMA and IL-6. CONCLUSIONS/
interpretationIn adolescents, physical activity is inversely related to HOMA and IL-6, independently of adiposity and fat localisation. These relationships are not accounted for by adipokines.
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