ArticleRNA (New York, N.Y.)2006
The fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2.
Article in RNA (New York, N.Y.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- Division of labor in trypanosome RNA processing and export through expanded Mex67 paralogs.Nucleic acids research · 2026Article
- Sending the message: specialized RNA export mechanisms in trypanosomes.Trends in parasitology · 2022Review
- m6A Methylation in Cardiovascular Diseases: From Mechanisms to Therapeutic Potential.Frontiers in genetics · 2022Review
- The RNA Binding Proteins YTHDC1 and FMRP Regulate the Nuclear Export ofJournal of virology · 2021Article
- The RNA-binding protein FMRP facilitates the nuclear export ofThe Journal of biological chemistry · 2019Article
- The Fragile X Protein and Genome Function.Molecular neurobiology · 2019Review
- Cytoplasmic localization of SBR (Dm NXF1) protein and its zonal distribution in the ganglia of Drosophila melanogaster larvae.Invertebrate neuroscience : IN · 2016Article
- Functional significance of the sex chromosomes during spermatogenesis.Reproduction (Cambridge, England) · 2015Review
- Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice.Frontiers in behavioral neuroscience · 2015Article
- Multiple cancer testis antigens function to support tumor cell mitotic fidelity.Molecular and cellular biology · 2012Article
- Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.Brain research · 2012Review
- The kinesin superfamily protein KIF17: one protein with many functions.Biomolecular concepts · 2012Article
- Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis.Molecular reproduction and development · 2011Article
- Cell-based analysis of structure-function activity of threonine aspartase 1.The Journal of biological chemistry · 2011Article
- Short- and long-term memory are modulated by multiple isoforms of the fragile X mental retardation protein.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.The Journal of biological chemistry · 2009Article
- Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element.Nucleic acids research · 2009Article
- Inactivation of Nxf2 causes defects in male meiosis and age-dependent depletion of spermatogonia.Developmental biology · 2009Article
- The fragile X mental retardation protein in circadian rhythmicity and memory consolidation.Molecular neurobiology · 2009Review
- Fragile X mental retardation protein FMRP binds mRNAs in the nucleus.Molecular and cellular biology · 2009Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss of fragile X mental retardation protein, FMRP, causes the fragile X syndrome. Highly expressed in the brain and testis, FMRP has been implicated in the transport and translation of specific mRNAs. Here we show that FMRP and the mRNA nuclear export factor NXF2 co-express in the mouse male germ cells and hippocampal neurons and that FMRP associates with NXF2 but not with its close relative NXF1. We thus hypothesize that FMRP and NXF2 may act in concert to promote the nucleocytoplasmic transport of specific mRNAs in male germ cells and neurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.