Evidence map›Paper›PMID 16790459›Full record

ArticleBMJ (Clinical research ed.)2006

Risk in primary care of colorectal cancer from new onset rectal bleeding: 10 year prospective study.

Jennifer du Toit, William Hamilton, Kevin Barraclough

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Systematic review of clinical features of suspected colorectal cancer in primary care.Canadian family physician Medecin de famille canadien · 2014
    Pooled it
  2. Pooled it
  3. The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011
    Pooled it
  4. Positive predictive values of ≥5% in primary care for cancer: systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
    Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Review
  9. Article
  10. Clinical features of bowel disease in patients aged <50 years in primary care: a large case-control study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017
    Observational
  11. General practice by numbers: presentation to final outcome.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Article
  12. Clinical features of bladder cancer in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
    Article
  13. Cancer diagnosis in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
    Review
  14. Five misconceptions in cancer diagnosis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2009
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jennifer du ToitHoyland House, Painswick, Gloucestershire GL6 6RD.
William Hamilton
Kevin Barraclough

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo measure the risk of colorectal cancer and adenoma with new onset rectal bleeding reported to primary care.

designCohort study.

settingA rural general practice in the United Kingdom.

participantsPatients aged 45 or more with new onset rectal bleeding, irrespective of other symptoms.

main outcome measuresPercentage of participants in whom colorectal cancer or colonic adenoma was identified after investigation of the bowel.

resultsDuring a 10 year period, 265 patients reported new rectal bleeding. Of these, 15 (5.7%, 95% confidence interval 3.2% to 9.2%) had colorectal cancer, and 13 (4.9%, 2.6% to 8.4%) had colonic adenoma. Only two of the patients with cancer had had diarrhoea.

conclusionsOne in 10 patients aged 45 or more with new onset rectal bleeding had colonic neoplasia, so investigation of the bowel should be offered to all such patients, whether or not they have other symptoms.

Indexed as

AdenomaAgedCohort StudiesColorectal NeoplasmsFamily PracticeGastrointestinal HemorrhageHumansMiddle AgedProspective StudiesRectal DiseasesRisk FactorsRural Health

Identifiers

PMID16790459
PMCPMC1489264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.