Evidence map›Paper›PMID 16786046›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2006

Immunology and homeopathy. 3. Experimental studies on animal models.

Paolo Bellavite, Riccardo Ortolani, Anita Conforti

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
14.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  5. Testing homeopathy in mouse emotional response models: pooled data analysis of two series of studies.Evidence-based complementary and alternative medicine : eCAM · 2012
    Article
  6. Article
  7. Article
  8. Postconditioning hormesis put in perspective: an overview of experimental and clinical studies.Dose-response : a publication of International Hormesis Society · 2011
    Article
  9. Article
  10. Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation.Evidence-based complementary and alternative medicine : eCAM · 2011
    Article
  11. Article
  12. Article
  13. Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2009
    Article
  14. Brief homeopathic pathogenetic experimentation: a unique educational tool in Brazil.Evidence-based complementary and alternative medicine : eCAM · 2009
    Article
  15. Dynamized preparations in cell culture.Evidence-based complementary and alternative medicine : eCAM · 2009
    Article
  16. Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma.Evidence-based complementary and alternative medicine : eCAM · 2008
    Article
  17. Immunology and homeopathy. 5. The rationale of the 'Simile'.Evidence-based complementary and alternative medicine : eCAM · 2007
    Article
  18. Immunology and homeopathy. 4. Clinical studies-part 2.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  19. Immunology and homeopathy. 4. Clinical studies-part 1.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Paolo BellaviteDepartment of Scienze Morfologico-Biomediche, University of Verona, Piazza L.A. Scuro, 37134 Verona, Italy. paolo.bellavite@univr.it
Riccardo Ortolani
Anita Conforti
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A search of the literature and the experiments carried out by the authors of this review show that there are a number of animal models where the effect of homeopathic dilutions or the principles of homeopathic medicine have been tested. The results relate to the immunostimulation by ultralow doses of antigens, the immunological models of the 'simile', the regulation of acute or chronic inflammatory processes and the use of homeopathic medicines in farming. The models utilized by different research groups are extremely etherogeneous and differ as the test medicines, the dilutions and the outcomes are concerned. Some experimental lines, particularly those utilizing mice models of immunomodulation and anti-inflammatory effects of homeopathic complex formulations, give support to a real effect of homeopathic high dilutions in animals, but often these data are of preliminary nature and have not been independently replicated. The evidence emerging from animal models is supporting the traditional 'simile' rule, according to which ultralow doses of compounds, that in high doses are pathogenic, may have paradoxically a protective or curative effect. Despite a few encouraging observational studies, the effectiveness of the homeopathic prevention or therapy of infections in veterinary medicine is not sufficiently supported by randomized and controlled trials.

Identifiers

PMID16786046
PMCPMC1475939
OpenAlexW2136146746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.