ReviewEndocrine2006
Estrogen effects on neuronal morphology.
Review in Endocrine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 29 citations in OpenAlex.
- Sex differences in the neurobiology of epilepsy: a preclinical perspective.Neurobiology of disease · 2014Review
- A sex- and region-specific role of Akt1 in the modulation of methamphetamine-induced hyperlocomotion and striatal neuronal activity: implications in schizophrenia and methamphetamine-induced psychosis.Schizophrenia bulletin · 2014Article
- Estradiol-dependent modulation of serotonergic markers in auditory areas of a seasonally breeding songbird.Behavioral neuroscience · 2012Article
- Estrogen receptor alpha inhibits the estrogen-mediated suppression of HIV transcription in astrocytes: implications for estrogen neuroprotection in HIV dementia.AIDS research and human retroviruses · 2009Article
- 17beta-estradiol protects against hypoxic/ischemic white matter damage in the neonatal rat brain.Journal of neuroscience research · 2009Article
- Rapid seasonal-like regression of the adult avian song control system.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons.Endocrine · 2007Article
- Astrocytic reaction to a lesion, under hormonal deprivation.Neuroscience letters · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
This review focuses on the effects of estrogen on neuronal morphology. Over the last decade neuroscientists have accumulated a wealth of information confirming the trophic effects of 17beta-estradiol on a variety of brain regions, including changes of hippocampal spine density and axonal outgrowth and retraction in hypothalamic nuclei, as well as other measures of structural reorganization that could underlie some of the cognitive benefits attributed to this hormone. Overall, results from a variety of investigators suggest that 17beta-estradiol is a potent structural signal that can drive developmental as well as adult plastic events in a variety of brain regions, not only those implicated in reproduction, but also in a diversity of functions. Most notably, these structural modifications that subserve cyclic physiological processes, can also be activated in other brain regions to protect and even reverse structural neurodegenerative processes. The data presented here are not exhaustive, but rather meant to provide a few examples of these structural effects of 17beta-estradiol that could have important implications for clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.