ArticleJournal of clinical microbiology1991
Restriction fragment analysis of a Candida tropicalis outbreak of sternal wound infections.
Article in Journal of clinical microbiology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Outbreaks of Fungal Infections in Hospitals: Epidemiology, Detection, and Management.Journal of fungi (Basel, Switzerland) · 2023Review
- Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?Clinical microbiology reviews · 2017Review
- Novel Polymorphic Multilocus Microsatellite Markers to Distinguish Candida tropicalis Isolates.PloS one · 2016Article
- The ins and outs of DNA fingerprinting the infectious fungi.Clinical microbiology reviews · 2000Review
- Elucidating the origins of nosocomial infections with Candida albicans by DNA fingerprinting with the complex probe Ca3.Journal of clinical microbiology · 1999Article
- Molecular and epidemiological characterization of vaginal Saccharomyces cerevisiae isolates.Journal of clinical microbiology · 1999Article
- Trends in antifungal use and epidemiology of nosocomial yeast infections in a university hospital.Journal of clinical microbiology · 1999Article
- Development of two species-specific fingerprinting probes for broad computer-assisted epidemiological studies of Candida tropicalis.Journal of clinical microbiology · 1996Article
- Use of random amplified polymorphic DNA as a typing method for Candida albicans in epidemiological surveillance of a burn unit.Journal of clinical microbiology · 1995Article
- Investigation of Candida albicans transmission in a surgical intensive care unit cluster by using genomic DNA typing methods.Journal of clinical microbiology · 1995Article
- Strain relatedness of Candida albicans strains isolated from children with leukemia and their bedside parents.Journal of clinical microbiology · 1994Article
- Investigation of the sequence of colonization and candidemia in nonneutropenic patients.Journal of clinical microbiology · 1994Article
- Epidemiological typing of Moraxella catarrhalis by using DNA probes.Journal of clinical microbiology · 1993Article
- Genotypic identification and characterization of species and strains within the genus Candida by using random amplified polymorphic DNA.Journal of clinical microbiology · 1992Article
- Laboratory aids in the diagnosis of invasive candidiasis.Mycopathologia · 1992Review
- Clamped homogeneous electric field gel electrophoresis typing of Torulopsis glabrata isolates causing nosocomial infections.Journal of clinical microbiology · 1992Article
- Restriction endonuclease analysis of Aspergillus fumigatus DNA.Journal of clinical pathology · 1992Article
- Impact of the changing epidemiology of fungal infections in the 1990s.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1992Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An apparent single-source outbreak of Candida tropicalis sternal wound infections in eight patients was investigated by utilizing DNA restriction fragment analysis (RFA) with HindIII and BstNI. All eight outbreak isolates appeared to be identical and were easily differentiated from control isolates by DNA RFA. Compared with an arbitrarily selected reference outbreak isolate, greater than or equal to 95% of the bands in the restriction digests identified by a computerized image analysis system from each of the outbreak isolates were identical versus 13 to 53% of the bands in any of the nine control isolates. Outbreak strains were significantly more likely to match the reference outbreak isolate than were controls (P less than 0.0001). The RFA was greatly facilitated by the use of computerized image analysis and confirmed the epidemiologic link between a scrub nurse and the infected patients.
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