ArticleCell2006
P-bodies react to stress and nonsense.
Article in Cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- MicroRNA (miRNA): A New Dimension in the Pathogenesis of Antiphospholipid Syndrome (APS).International journal of molecular sciences · 2020Review
- The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation.PLoS pathogens · 2019Article
- Heat-induced ribosome pausing triggers mRNA co-translational decay in Arabidopsis thaliana.Nucleic acids research · 2015Article
- Pleiotropic modes of action in tumor cells of RNASET2, an evolutionary highly conserved extracellular RNase.Oncotarget · 2015Article
- A global profiling of uncapped mRNAs under cold stress reveals specific decay patterns and endonucleolytic cleavages in Brachypodium distachyon.Genome biology · 2013Article
- A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi.Protein & cell · 2011Article
- MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6.Nucleic acids research · 2011Article
- The yeast Cbk1 kinase regulates mRNA localization via the mRNA-binding protein Ssd1.The Journal of cell biology · 2011Article
- Article
- Requirements for nuclear localization of the Lsm2-8p complex and competition between nuclear and cytoplasmic Lsm complexes.Journal of cell science · 2007Article
- Components of the Arabidopsis mRNA decapping complex are required for early seedling development.The Plant cell · 2007Article
- XRN 5'→3' exoribonucleases: structure, mechanisms and functions.Biochimica et biophysica actaReview
Corrections and comments
- Comment on
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.
Indexed as
Identifiers
16777595What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.