Evidence map›Paper›PMID 16774693›Full record

ReviewArthritis research & therapy2006

Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data.

Christina D Chambers, Zuhre N Tutuncu, Diana Johnson, Kenneth L Jones

Abstract readReview
In one paragraph

Review in Arthritis research & therapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Old and New Calcineurin Inhibitors in Lupus Nephritis.Journal of clinical medicine · 2021
    Review
  6. Review
  7. Article
  8. Rheumatologic Medication Use During Pregnancy.Obstetrics and gynecology · 2020
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. The safety of ketoprofen in different ages.Journal of pharmacology & pharmacotherapeutics · 2013
    Article
  15. Review
  16. Safety of biologic therapy in rheumatoid arthritis.Nature reviews. Rheumatology · 2011
    Review
  17. Review
  18. Review
  19. Management of RA medications in pregnant patients.Nature reviews. Rheumatology · 2009
    Review
  20. Therapy: are TNF inhibitors safe in pregnancy?Nature reviews. Rheumatology · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christina D ChambersDepartment of Pediatrics, University of California, San Diego, CA, USA. chchambers@ucsd.edu
Zuhre N Tutuncu
Diana Johnson
Kenneth L Jones

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For female patients with rheumatoid arthritis, the availability of a host of new disease modifying antirheumatic drugs has raised important questions about fetal safety if a woman becomes pregnant while she is being treated. In addition, there is limited safety information regarding many of the older medications commonly used to treat rheumatoid arthritis in women of reproductive age. Current summary pregnancy risk information for selected medications used to treat rheumatoid arthritis is reviewed in the context of the pregnancy label category. In addition, the strengths and weaknesses of post-marketing strategies for developing new pregnancy safety information are described.

Indexed as

Product Surveillance, PostmarketingAnti-Inflammatory AgentsAntirheumatic AgentsArthritis, RheumatoidFemaleHumansPregnancyPregnancy ComplicationsAnti-Inflammatory AgentsAntirheumatic Agents

Identifiers

PMID16774693
PMCPMC1779429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.