Evidence map›Paper›PMID 16773496›Full record

ReviewThe Journal of membrane biology

Hair cells--beyond the transducer.

G D Housley, W Marcotti, D Navaratnam, E N Yamoah

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in The Journal of membrane biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 87 citations in OpenAlex.

  1. Quantitative FluorescentFrontiers in cellular neuroscience · 2021
    Article
  2. Article
  3. Article
  4. Hair Cell Afferent Synapses: Function and Dysfunction.Cold Spring Harbor perspectives in medicine · 2019
    Review
  5. Article
  6. Purinergic Signaling and Cochlear Injury-Targeting the Immune System?International journal of molecular sciences · 2019
    Review
  7. Article
  8. Study of the Mechanisms by Which Aminoglycoside Damage Is Prevented in Chick Embryonic Hair Cells.Journal of the Association for Research in Otolaryngology : JARO · 2019
    Article
  9. Article
  10. Fast CaFrontiers in molecular neuroscience · 2018
    Article
  11. Article
  12. Global Analysis of Protein Expression of Inner Ear Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  13. Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Purinergic neuron-glia interactions in sensory systems.Pflugers Archiv : European journal of physiology · 2014
    Review
  20. Regenerated synapses between postnatal hair cells and auditory neurons.Journal of the Association for Research in Otolaryngology : JARO · 2013
    Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

G D HousleyDepartment of Physiology, University of Auckland, Private Bag, 92019, Auckland, New Zealand. g.housley@auckland.ac.nz
W Marcotti
D Navaratnam
E N Yamoah
University of Auckland · NZUniversity of California, Davis · USUniversity of Sheffield · GBYale University · US

Funding

Potassium Homeostasis in the Inner EarR01DC007592 · NIDCD · UNIVERSITY OF NEVADA RENO · PI YAMOAH, EBENEZER N · 2005 to 2014
$4.5M
FUNCTIONAL PROPERTIES OF CA PUMPS IN HAIR CELLR01DC004215 · NIDCD · UNIVERSITY OF CINCINNATI · PI YAMOAH, EBENEZER N. · 1999 to 2003
$1.0M
NIDCD NIH HHS DC03828NIDCD NIH HHS DC07592NIDCD NIH HHS R01 DC004215
6 · The paper itself

Abstract

overviewThis review considers the "tween twixt and twain" of hair cell physiology, specifically the signaling elements and membrane conductances which underpin forward and reverse transduction at the input stage of hair cell function and neurotransmitter release at the output stage. Other sections of this review series outline the advances which have been made in understanding the molecular physiology of mechanoelectrical transduction and outer hair cell electromotility. Here we outline the contributions of a considerable array of ion channels and receptor signaling pathways that define the biophysical status of the sensory hair cells, contributing to hair cell development and subsequently defining the operational condition of the hair cells across the broad dynamic range of physiological function.

Indexed as

AnimalsHair Cells, Auditory, InnerHair Cells, Auditory, OuterMembrane PotentialsModels, BiologicalPotassium ChannelsReceptors, PurinergicSignal TransductionPotassium ChannelsReceptors, Purinergic

Identifiers

PMID16773496
OpenAlexW1966389722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.