Evidence map›Paper›PMID 16773402›Full record

ArticlePediatric nephrology (Berlin, Germany)2006

Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement.

John D Mahan, Bradley A Warady, Consensus Committee

Registry-linked trialAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00943995 (TIW Growth Hormone Therapy in Children on Hemodialysis), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00943995 phase3completednot on this mapstarted 2010, after this paper: background citation

TIW Growth Hormone Therapy in Children on Hemodialysis

TypeinterventionalSponsorNationwide Children's HospitalRan2010 to 2012Enrolled3ConditionsKidney Failure, Chronic, Renal DialysisArmssomatropin
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 186 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. End-stage kidney disease in infancy: an educational review.Pediatric nephrology (Berlin, Germany) · 2020
    Review
  18. Article
  19. Review
  20. Treatment of Growth Retardation in a Child with CKD.Clinical journal of the American Society of Nephrology : CJASN · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

John D MahanDepartment of Pediatrics, Division of Pediatric Nephrology, The Ohio State University COMPH, Columbus, OH, USA. MahanJ@pediatrics.ohio-state.edu
Bradley A Warady
Consensus Committee
Children's Mercy Hospital · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth failure is a clinically important issue in children with chronic kidney disease (CKD) and is associated with significant morbidity and mortality. Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH)-insulin-like growth factor-I (IGF-I) axis, malnutrition, acidosis, and renal bone disease. The management of growth failure in children with CKD is complicated by the presence of other disease-related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, some practitioners and families have been reluctant to institute GH therapy, citing an unwillingness to comply with daily injections, reimbursement difficulties, or impending renal transplantation. Suboptimal attention to growth failure management may be further compounded by a lack of clinical guidelines for the appropriate assessment and treatment of growth failure in these children. This review of growth failure in children with CKD concludes with an algorithm developed by members of the consensus committee, outlining their recommendations for appropriate steps to improve growth and overall health outcomes in children with CKD.

Indexed as

Body HeightChildGrowth DisordersHuman Growth HormoneHumansInfantInsulin-Like Growth Factor IKidney Failure, ChronicKidney TransplantationRecombinant ProteinsRenal DialysisHuman Growth HormoneInsulin-Like Growth Factor IRecombinant Proteins

Identifiers

PMID16773402
OpenAlexW2009839356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.