Evidence map›Paper›PMID 16773393›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2006

Invasive meningococcal disease in children in Greece: comparison of serogroup A disease with disease caused by other serogroups.

M N Tsolia, M Theodoridou, G Tzanakaki, V Vlachou, G Mostrou, F Stripeli, P Kalabalikis, A Pangalis, D Kafetzis, J Kremastinou and 1 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Meningococcal serogroup Y emergence in Europe: update 2011.Human vaccines & immunotherapeutics · 2012
    Article
  8. Article
  9. Hospital-based surveillance of meningococcal meningitis in Salvador, Brazil.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2007
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M N TsoliaSecond Dept of Pediatrics P. and A. Kyriakou Children's Hospital, University of Athens School of Medicine, Thivon and Levadias St., 115 27, Athens, Greece. matsolia@ath.forthnet.gr
M Theodoridou
G Tzanakaki
V Vlachou
G Mostrou
F Stripeli
P Kalabalikis
A Pangalis
D Kafetzis
J Kremastinou
A Konstantopoulos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although invasive meningococcal disease caused by serogroup A is not prevalent in developed countries, a considerable number of cases were recently recorded in Greece. In this study, serogroup A meningococcal disease was compared prospectively with meningococcal disease caused by other serogroups, using similar settings of testing and management during a 5-year period between 1999 and 2003. The Neisseria meningitidis serogroup was determined in 262 cases. Serogroup B predominated, accounting for 158 (60%) of the cases. Serogroup A was second most frequent (19%), followed by serogroups W135 (11%), C (8%), and Y (2%). No cases due to serogroup C were recorded during the last year of the study. Patients with serogroup A disease were older and had a milder course compared to patients infected with serogroups B or C. Toxic appearance, purpura, thrombocytopenia, abnormal coagulation tests, and the need for admission to the intensive care unit, fluid resuscitation, inotropic drugs, and mechanical ventilation were less common. Although morbidity and mortality were lower in these patients, the differences were not significant. Serogroup B is predominant in our area, and the introduction of an effective vaccine against it is a priority. Serogroup A has emerged as the second most common serogroup, but the illness associated with it is milder.

Indexed as

Neisseria meningitidis, Serogroup AAdolescentChildChild, PreschoolFemaleGreeceHumansInfantMaleMeningococcal InfectionsNeisseria meningitidis, Serogroup BNeisseria meningitidis, Serogroup CNeisseria meningitidis, Serogroup W-135Treatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.