Evidence map›Paper›PMID 16773306›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2006

Early satiety in cancer patients: a common and important but underrecognized symptom.

Mellar P Davis, Declan Walsh, Ruth Lagman, Tugba Yavuzsen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. The determinants of reduced dietary intake in hospitalised colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  7. Cancer cachexia: impact, mechanisms and emerging treatments.Journal of cachexia, sarcopenia and muscle · 2013
    Article
  8. Animal models of the cancer anorexia-cachexia syndrome.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011
    Review
  9. Article
  10. Components of the anorexia-cachexia syndrome: gastrointestinal symptom correlates of cancer anorexia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2009
    Article
  11. A questionnaire study of the approach to the anorexia-cachexia syndrome in patients with cancer by staff in a district general hospital.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2009
    Article
  12. Neurobiology of inflammation-associated anorexia.Frontiers in neuroscience · 2009
    Article
  13. The silent symptom early satiety: a forerunner of distinct phenotypes of anorexia/cachexia syndromes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2006
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mellar P DavisThe Harry R Horvitz Center For Palliative Medicine, The Cleveland Clinic Taussig Cancer Center, Cleveland, OH, USA.
Declan Walsh
Ruth Lagman
Tugba Yavuzsen
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe severity of anorexia correlates with the presence of early satiety. The sense of fullness limits nutritional intake. The symptom is poorly understood because most assessment questionnaires do not include early satiety.

methodsPatients rarely volunteer early satiety. Central and peripheral mechanisms may be involved in the genesis of early satiety. These would include central sensory specific satiety, food aversions, diurnal changes in intake, gastric motility and accommodation and as gastrointestinal hormones.

conclusionsProkinetic medications, such as metoclopramide are used to treat early satiety. However, other medications which influence gastric accommodation such as clonidine, sumatriptan, or sildenafil, or diminish enteric afferent output such as kappa opioid receptor agonists, may favorably influence early satiety and should be subject to future research. Translational research is needed to understand the relationship of early satiety to gastric motility and accommodation.

Indexed as

Satiety ResponseAnorexiaCircadian RhythmEnergy IntakeGastrointestinal TransitHumansNeoplasmsPrevalenceSeverity of Illness IndexSickness Impact Profile

Identifiers

PMID16773306
OpenAlexW1980411778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.