ReviewBriefings in functional genomics & proteomics2006
Mass spectrometry of RNA: linking the genome to the proteome.
Review in Briefings in functional genomics & proteomics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- tRNA modifications: greasing the wheels of translation and beyond.RNA biology · 2025Review
- Unravelling Strain-Specific Modifications of Toxoplasma gondii tRNA and sncRNA Using LC-MS/MS.Microbiology spectrum · 2023Article
- Elucidating the Functions of Non-Coding RNAs from the Perspective of RNA Modifications.Non-coding RNA · 2021Review
- Compendium of Methods to Uncover RNA-Protein Interactions In Vivo.Methods and protocols · 2021Review
- Accurate inference of the full base-pairing structure of RNA by deep mutational scanning and covariation-induced deviation of activity.Nucleic acids research · 2020Article
- A general LC-MS-based RNA sequencing method for direct analysis of multiple-base modifications in RNA mixtures.Nucleic acids research · 2019Article
- Matching tRNA modifications in humans to their known and predicted enzymes.Nucleic acids research · 2019Article
- Identification of tRNA nucleoside modification genes critical for stress response and development in rice and Arabidopsis.BMC plant biology · 2017Article
- MicroRNA MultiTool: A Software for Identifying Modified and Unmodified Human microRNA Using Mass Spectrometry.Non-coding RNA · 2017Article
- RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids.Nucleic acids research · 2015Article
- Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.Nature protocols · 2014Article
- A system of RNA modifications and biased codon use controls cellular stress response at the level of translation.Chemical research in toxicology · 2014Article
- Analysis of RNA cleavage by MALDI-TOF mass spectrometry.Nucleic acids research · 2013Article
- Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin.Molecules (Basel, Switzerland) · 2011Article
- Use of specific chemical reagents for detection of modified nucleotides in RNA.Journal of nucleic acids · 2011Article
- A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.PLoS genetics · 2010Article
- Top-down identification and characterization of biomolecules by mass spectrometry.Journal of the American Society for Mass Spectrometry · 2008Review
- Mass spectrometry-based detection of transfer RNAs by their signature endonuclease digestion products.RNA (New York, N.Y.) · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Ribonucleic acids (RNAs) are continuing to attract increased attention as they are found to play pivotal roles in biological systems. Just as genomics and proteomics have been enabled by the development of effective analytical techniques and instrumentation, the large-scale analysis of non-protein coding (nc)RNAs will benefit as new analytical methodologies, such as mass spectrometry (MS), are developed for their analysis. Mass spectrometry offers a number of advantages for RNA analysis arising from its ability to provide mass and sequence information starting with limited amounts of sample. This review will highlight recent developments in the field of MS that enable the characterization of RNA modification status, RNA tertiary structures, and ncRNA expression levels. These developments will also be placed in perspective of how MS of RNAs can help elucidate the link between the genome and proteome.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.