Evidence map›Paper›PMID 16769629›Full record

ArticleProceedings. Biological sciences2006

Origins and evolution of the Europeans' genome: evidence from multiple microsatellite loci.

Elise M S Belle, Pierre-Alexandre Landry, Guido Barbujani

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  7. Maritime route of colonization of Europe.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  8. Review
  9. Article
  10. Ancestry of modern Europeans: contributions of ancient DNA.Cellular and molecular life sciences : CMLS · 2013
    Review
  11. Article
  12. Article
  13. Article
  14. Evolution of lactase persistence: an example of human niche construction.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2011
    Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elise M S BelleUniversità di Ferrara Dipartimento di Biologia Via Borsari 46, 44100 Ferrara, Italy.
Pierre-Alexandre Landry
Guido Barbujani

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is general agreement that the current European gene pool is mainly derived from Palaeolithic hunting-gathering and Neolithic farming ancestors, but different studies disagree on the relative weight of these contributions. We estimated admixture rates in European populations from data on 377 autosomal microsatellite loci in 235 individuals, using five different numerical methods. On average, the Near Eastern (and presumably Neolithic) contribution was between 46 and 66%, and admixture estimates showed, with all methods, a strong and significant negative correlation with distance from the Near East. If the assumptions of the model are approximately correct, i.e. if the Basques' and Near Easterners' genomes represent a good approximation to the Palaeolithic and Neolithic settlers of Europe, respectively, these results imply that half or more of the Europeans' genes are descended from Near Eastern ancestors who immigrated in Europe 10000 years ago. If these assumptions are incorrect, our results show anyway that clinal variation is the rule in the Europeans' genomes and that lower estimates of Near Eastern admixture obtained from the analysis of single markers do not reflect the patterns observed at the genomic level.

Indexed as

Evolution, MolecularGenome, HumanMicrosatellite RepeatsEuropeGene FlowGenetic DriftHumansPolymorphism, GeneticTandem Repeat Sequences

Identifiers

PMID16769629
PMCPMC1634924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.