Evidence map›Paper›PMID 16763912›Full record

ReviewJournal of inherited metabolic disease

Principles of therapeutic liver repopulation.

Markus Grompe

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of inherited metabolic disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Development of Ectopic Livers by Hepatocyte Transplantation Into Swine Lymph Nodes.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Human hepatocyte transplantation: current experience and future challenges.Nature reviews. Gastroenterology & hepatology · 2010
    Review
  12. Article
  13. Article
  14. Article
  15. Embryonic and induced pluripotent stem cells as a model for liver disease.Critical reviews in biomedical engineering · 2009
    Review
  16. Cultured rat hepatocytes upregulate Akt and ERK in an ErbB-2-dependent manner.American journal of physiology. Gastrointestinal and liver physiology · 2008
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Markus GrompeOregon Stem Cell Center, Oregon Health & Science University, Portland, Oregon, USA. grompem@ohsu.edu

Funding

Treatment of Distal Tyrosine Pathway DisordersR01DK048252 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI GROMPE, MARKUS · 1994 to 2017
$5.5M
TRANSPLANTATION ASSAY FOR LIVER REPOPULATING CELLSR01DK051592 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI GROMPE, MARKUS · 1997 to 2015
$4.8M
TRANSPLANTATION ASSAY FOR LIVER REPOPULATING CELLSR55DK051592 · NIDDK · OREGON HEALTH AND SCIENCE UNIVERSITY · PI GROMPE, MARKUS · 1996 to 1996
–
NIDDK NIH HHS DK-51592NIDDK NIH HHS R01 DK048252
6 · The paper itself

Abstract

Liver repopulation by transplanted hepatocytes is a promising approach for many inborn errors of metabolism. In this review, examples of liver repopulation in animals and the implications of these models for clinical cell transplantation will be discussed.

Indexed as

Liver RegenerationLiver TransplantationCell DifferentiationCell ProliferationHepatocytesHumansLiverMaleMetabolic Networks and PathwaysMetabolism, Inborn ErrorsSelection, GeneticTransplantation Conditioning

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.